CYP3A4 antibody

Principal name

CYP3A4 antibody

Alternative names for CYP3A4 antibody

CYP3A3, Cytochrome P450 3A4, CYPIIIA4, Nifedipine oxidase, Cytochrome P450 3A3, CYPIIIA3, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Albendazole monooxygenase, Albendazole sulfoxidase, Quinine 3-monooxygenase, Taurochenodeoxycholate 6-alpha-hydroxylase

SwissProt ID

P08684 (Human)

Gene ID

1576 (CYP3A4)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Ms (Mouse), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep), Eq (Equine), Gt (Goat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Functional assay (FN), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F), Frozen Sections (C)

Background of CYP3A4 antibody

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

General readings

General / background references:Guengerich FP Cytochrome P-450 3A4: regulation and role in drug metabolism. Annu Rev Pharmacol Toxicol 39:1-17 (1999). PubMed PMID: 10331074
Szklarz GD & Halpert JR Molecular basis of P450 inhibition and activation: implications for drug development and drug therapy. Drug Metab Dispos 26:1179-84 (1998). PubMed PMID: 9860924

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYP3A4 antibody

Immunofluorescence analysis of HepG2 cells using CYP3A4 Mouse mAb Cat.-No AM06743PU-N (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Mouse IgG1 3H8 Purified Hu E, F, ICC/IF, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CYP3A4 antibody

Immunoperoxidase of purified MaxPab antibody to CYP3A4 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CYP3A4 antibody

Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 3A4/5 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP3A4 antibody

Western blot analysis of extracts from K562 cells, using P450 3A4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP3A4 antibody

Western blot analysis of Human fetal liver tissue using TA324141(CYP3A4 Antibody) at dilution 1/250 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP3A4 antibody

Predicted band size: 57 kDa . Positive control: Mouse liver tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP3A4 antibody

WB Suggested Anti-CYP3A4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human kidney Rabbit IgG Purified Bov, Can, GP, Hu, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

CYP3A4 antibody

WB Suggested Anti-CYP3A4 Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

CYP3A4 (+ CYP3A5) antibody

Western blot(WB) analyzes of CYP3A4/5 antibody (Cat.-No.: AP06777PU-N) in extracts from Jurkat cells Rabbit Aff - Purified Hu ICC/IF, P, WB

Regular Price: 0.1 mg / €350.00

Special Price: 0.1 mg / €224.00

  Acris Antibodies GmbH

CYP3A4 antibody

Western blot analysis of anti-CYP3A4 Antibody (Center) in NCI-H460 cell line lysates (35ug/lane). CYP3A4 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CYP3A4 antibody

CYP3A4 Rabbit Azide Free Hu FN, WB
50 µl / €400.00
  Acris Antibodies GmbH

CYP3A4 antibody

CYP3A4 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CYP3A4 antibody

Western Blot analysis of CYP3A4 expression in transfected 293T cell line (H00001576-T01) by CYP3A4 MaxPab polyclonal antibody.

Lane 1: CYP3A4 transfected lysate(57.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CYP3A4 antibody

CYP3A4 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

CYP3A4 antibody

Lane 1 : molecular weight markers.
Lane 2 : CYP3A4 -100 ng.
Lane 3 : CYP3A4-300 ng. Rabbit Hu WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

CYP3A4 antibody

Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 3A4/5 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

CYP3A4 antibody

Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 3A4/5 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

CYP3A4 antibody

CYP3A4 Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

CYP3A4 antibody

CYP3A4 Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

CYP3A4 (Center) antibody

Human kidney; WB Suggested Anti-CYP3A4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human kidney; CYP3A4 antibody - middle region (ARP51348_P050) in Human kidney cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

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