CYP7A1 antibody

Principal name

CYP7A1 antibody

Alternative names for CYP7A1 antibody

Cytochrome P450 7A1, CYP7, CYPVII, Cholesterol 7-alpha-monooxygenase, Cholesterol 7-alpha-hydroxylase

SwissProt ID

O46491 (Pig), P18125 (Rat), P22680 (Human), P51542 (Rabit), Q64505 (Mouse)

Gene ID

1581 (CYP7A1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of CYP7A1 antibody

CYP7A1 (Cytochrome P450 Subfamily VIIA Polypeptide 1), also called CYP7 or CHOLESTEROL 7-ALPHA-HYDROXYLASE, is an enzyme that in humans is encoded by the CYP7A1 gene. Using both mouse-human somatic cell hybrids and in situ chromosomal hybridization, Cohen et al. (1992) mapped the CYP7 gene to 8q11-q12. By transfection of reporter constructs, mutation analysis, and DNase footprinting, Molowa et al. (1992) identified areas of the CYP7A1 promoter region that showed hepatocyte-specific activation. They found HNF3 to be an activator of CYP7A1 activity. Agellon et al. (2002) found that wildtype mice and mice transgenic for human CYP7A1 respond differently to cholesterol feeding. Cholesterol feeding stimulated Cyp7a1 mRNA abundance and enzymatic activity in wildtype mice, but repressed human CYP7A1 mRNA and activity in transgenic mice.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYP7A1 (C-term) antibody

Western blot analysis of anti-CYP7A1 Antibody (C-term) in K562 cell line lysates (35ug/lane). CYP7A1(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CYP7A1 antibody

CYP7A1 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CYP7A1

CYP7A1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CYP7A1

CYP7A1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

CYP7A1

CYP7A1 Human
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CYP7A1 overexpression lysate

CYP7A1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

6 Item(s)

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