CYR61 antibody

Principal name

CYR61 antibody

Alternative names for CYR61 antibody

CCN1, GIG1, IGFBP10, IBP10, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IGF-binding protein 10, CCN family member 1

SwissProt ID

O00622 (Human), P18406 (Mouse), Q9ES72 (Rat)

Gene ID

3491 (CYR61), 16007 (Cyr61), 83476

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Sh (Sheep), Chk (Chicken), Xen (Xenopus), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CYR61 antibody

Cysteine-rich angiogenic inducer 61(CYR61) or CCN family member 1(CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. This gene is mapped to 1p22.3. CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYR61 antibody

  Rabbit Polyclonal CYR61 Antibody  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CYR61 rabbit polyclonal antibody. (TA590733) Rabbit IgG Purified Hu, Mky, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYR61 antibody

  Rabbit Polyclonal CYR61 Antibody  
Immunohistochemistry: CYR61 antibody - Human endometrium.  Photo courtesy of Dr. rer. nat. Isabella Gashaw, Universität Duisburg-Essen Rabbit Purified Hu C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYR61 antibody

  Rabbit Polyclonal Anti-CYR61 Antibody  
Host: Rabbit; Target Name: CYR61; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 3.0ug/ml Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYR61 antibody

  Rabbit Polyclonal anti-CYR61 Antibody  
Human Colon stained with anti-CYR61 antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYR61 antibody

Immunohistochemistry: AM09007PU-N CYR61 antibody staining of Human Breast Cancer Tissue Paraffin Embedded Sections at 1/50 dilution for 2 hours at RT. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). Mouse IgG1 3H3 Purified Hu E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

CYR61 antibody

Immunohistochemistry: AM09007PU-N CYR61 antibody staining of Human Breast Cancer Tissue Paraffin Embedded Sections at 1/50 dilution for 2 hours at RT. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). Mouse IgG1 3H3 Purified Hu E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

CYR61 Control Peptide

CYR61 Purified
50 µg / €190.00
  Acris Antibodies GmbH

CYR61 antibody

Western blot analysis of Cyr 61 expression with lysate from Jurkat cells (Lane 1) and mouse small intestine tissue (Lane 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 3. Sample of the transition zone in human hip osteonecrosiss: A 1/500 dilution of AP02087SU was incubated 4h at room temprature with fixed cells (with permission from J Orthop Res (Radke et al., 2006). Rabbit Serum Hu C, P, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 3. Sample of the transition zone in human hip osteonecrosiss: A 1/500 dilution of AP02087SU was incubated 4h at room temprature with fixed cells (with permission from J Orthop Res (Radke et al., 2006). Rabbit Serum Hu C, P, WB
20 µl / €170.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 1. Samples from ovine fracture callus. A 1/500 dilution of antibody was used. Figure with permission by J Orthop Res (Lienau et al., 2006) Rabbit Serum Hu, Rt, Sh C, P, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 1. Samples from ovine fracture callus. A 1/500 dilution of antibody was used. Figure with permission by J Orthop Res (Lienau et al., 2006) Rabbit Serum Hu, Rt, Sh C, P, WB
20 µl / €170.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CYR61 - human gene knockout kit via CRISPR

CYR61 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CYR61 - human gene knockout kit via CRISPR

CYR61 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYR61 - human gene knockout kit via CRISPR

CYR61 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYR61 - human gene knockout kit via CRISPR

CYR61 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CYR61

  Purified recombinant protein of Human cysteine-rich, angiogenic inducer, 61 (CYR61).  
CYR61 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

CYR61

CYR61 Human Purified > 95 % pure by SDS-PAGE gel and HPLC analyses E. coli
20 µg / €230.00
  Acris Antibodies GmbH

CYR61

CYR61 Human Purified > 95 % pure by SDS-PAGE gel and HPLC analyses E. coli
5 µg / €140.00
  Acris Antibodies GmbH

ELISA Kits

Catalog No.    

Human CYR61/CCN1 ELISA Kit

Human CYR61/CCN1 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

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