CYR61 antibody

Principal name

CYR61 antibody

Alternative names for CYR61 antibody

CCN1, GIG1, IGFBP10, IBP10, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IGF-binding protein 10, CCN family member 1

SwissProt ID

O00622 (Human), P18406 (Mouse), Q9ES72 (Rat)

Gene ID

3491 (CYR61), 16007 (Cyr61)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Xen (Xenopus), Sh (Sheep), Mky (Monkey)

Available hosts

Rabbit, Chicken, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Neutralisation (NEUT)

Background of CYR61 antibody

CCN1 (cysteine-rich 61 or CYR61), a ubiquitous angiogenic factor, is a member of the CNN family, which is also comprised of CTGF, WISP-1, WISP-2, and WISP-3. It is a multidomain protein, containing one each of CTCK, IGFBP, TSP type-1, and VWFC domains. CCN1 is associated with the extracellular matrix and functions as a ligand for integrin receptors. It is expressed in response to growth factor stimulation, and mediates various cellular processes, including cell adhesion, migration, proliferation, angiogenesis, extracellular-matrix remodeling, and placental development. Previous studies have indicated that it may also play a role in wound healing by influencing the expression of genes required for this process, such as TIMP1, PAI-1, VEGA-A, VEGA-C, MMP1, MMP3, and uPA. CCN1 has also been implicated in breast cancer.

General readings

Tong X., et al. (2004) Oncogene. 23(28):4847-55
Latinkic BV., et al. (2003) Development. 130(11):2429-41
Grzeszkiewicz TM., et al. (2001) J Biol Chem. 276(24):21943-50

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYR61 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CYR61 rabbit polyclonal antibody. (TA590733) Rabbit IgG Purified Hu, Mky, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYR61 antibody

AP15515PU CYR61 antibody staining of Human Colon. Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

CYR61 antibody

AP15515PU CYR61 antibody staining of Human Colon. Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

CYR61 antibody

AP15515PU CYR61 antibody staining of Human Colon. Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

CYR61 antibody

Immunohistochemistry: CYR61 antibody - Human endometrium.  Photo courtesy of Dr. rer. nat. Isabella Gashaw, Universität Duisburg-Essen Rabbit Purified Hu C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYR61 antibody

Immunohistochemistry: AM09007PU-N CYR61 antibody staining of Human Breast Cancer Tissue Paraffin Embedded Sections at 1/50 dilution for 2 hours at RT. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). Mouse IgG1 3H3 Purified Hu E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

CYR61 antibody

Immunohistochemistry: AM09007PU-N CYR61 antibody staining of Human Breast Cancer Tissue Paraffin Embedded Sections at 1/50 dilution for 2 hours at RT. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). Mouse IgG1 3H3 Purified Hu E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

CYR61 Control Peptide

CYR61 Purified
50 µg / €190.00
  Acris Antibodies GmbH

CYR61 antibody

Western blot analysis of Cyr 61 expression with lysate from Jurkat cells (Lane 1) and mouse small intestine tissue (Lane 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 3. Sample of the transition zone in human hip osteonecrosiss: A 1/500 dilution of AP02087SU was incubated 4h at room temprature with fixed cells (with permission from J Orthop Res (Radke et al., 2006). Rabbit Serum Hu C, P, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 3. Sample of the transition zone in human hip osteonecrosiss: A 1/500 dilution of AP02087SU was incubated 4h at room temprature with fixed cells (with permission from J Orthop Res (Radke et al., 2006). Rabbit Serum Hu C, P, WB
20 µl / €170.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 1. Samples from ovine fracture callus. A 1/500 dilution of antibody was used. Figure with permission by J Orthop Res (Lienau et al., 2006) Rabbit Serum Hu, Rt, Sh C, P, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

CYR61 antibody

Figure 1. Samples from ovine fracture callus. A 1/500 dilution of antibody was used. Figure with permission by J Orthop Res (Lienau et al., 2006) Rabbit Serum Hu, Rt, Sh C, P, WB
20 µl / €170.00
  Acris Antibodies GmbH

CYR61 antibody

CYR61 Mouse IgG2a 3C11 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

CYR61 antibody

The cell lysate of Jurkat ( 40 µg ) was resolved by SDS-PAGE and probed with CYR61 monoclonal antibody, clone 3H3 ( Cat # MAB2043 ) ( 1: 250 ). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 3H3 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

CYR61 antibody

Staining of CYR61 on human endometrium using CYR61 polyclonal antibody ( Cat # PAB12525 ). Photo courtesy of Dr. rer. nat. Isabella Gashaw, University Duisburg-Essen. Rabbit Hu C, ICC/IF, P, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

CYR61 antibody

CYR61 Rabbit Hu WB
0.1 ml / €560.00
  Abnova Taiwan Corp.

CYR61 antibody

CYR61 Rabbit Chk, Hu, Xen WB
0.1 ml / €410.00
  Abnova Taiwan Corp.

CYR61 antibody

ELISA: CYR61 Antibody [26140002] Rabbit Hu E
50 µg / €500.00
  Novus Biologicals Inc.

CYR61 antibody

CYR61 Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

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