CYSLTR1 antibody

Principal name

CYSLTR1 antibody

Alternative names for CYSLTR1 antibody

Cysteinyl leukotriene receptor 1, CysLTR1, LTD4 receptor, HG55, HMTMF81, Cysteinyl leukotriene D4 receptor, G-protein coupled receptor HG55

SwissProt ID

Q2NNR5 (Cavpo), Q924T8 (Rat), Q95N02 (Pig), Q99JA4 (Mouse), Q9Y271 (Human)

Gene ID

10800 (CYSLTR1)

Available reactivities

GP (Guinea Pig), Hu (Human), Ms (Mouse), Rb (Rabbit), Bov (Bovine), Mky (Monkey), Por (Porcine), Rt (Rat), Gorilla, Bear

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of CYSLTR1 antibody

LTC4, LTD4, and LTE4 are leukotrienes (cys-LTs) derived from arachidonic acid as a result of immune or inflammatory stimuli. The above mentioned cys-LTs bind and activate two receptors belonging to the G-protein coupled receptor superfamily, CysLTR1 and CysLTR2 (also med cysLT1 and cysLT2 respectively). There is evidence though that other receptors are yet to be identified. These two receptors couple to both pertussis toxin sensitive (Gi/o) and insensitive (Gq, which initiates Ca2+ influx) G-proteins for their sigling. The G-protein coupled to is probably determined by which ligand binds the receptor as all three cys-LTs can activate the two receptors albeit with different affinities. In mouse, CysLTR1 and CysLTR2 are subject to altertive splicing. CysLTR1 receptor expresses greater affinity for LTD4 and binds equally to LTC4 and LTE4 whereas CysLTR2 has greater and equal affinity towards LTC4 and LTD4 over LTE4. Human CysLTR1 is highly expressed in spleen, peripheral blood, leukocytes. It is less strongly expressed in lung, small intestine, pancreas and hardly or not expressed in liver, colon, kidney, skeletal muscle, testis heart and brain. On the other hand, CysLTR2 is highly expressed in spleen and leukocytes. Its expression in the heart, brain, spil cord and adrel gland differs it from that of CysLTR1. Cys-LTs and their receptors are involved in respiratory diseases like asthma and other conditions such as cancer cardiovascular, gastrointestil, skin and immune disorders.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYSLTR1 antibody

Western blot analysis of mouse spleen lysate (Lanes 1 and 2: 49ug lysate) and Jurkat cells (Lanes 3 and 4: 54ug lysate) with anti-cysteinyl leukotriene receptor 1 antibody diluated at 1:2000. (Predicted and observed size: 39kDa) Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYSLTR1 antibody

Western blot analysis of extracts from COS7 cells, using CLTR1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYSLTR1 antibody

Western blot analysis of acute monocytic leukemia THP-1 (lanes 1 and 4), promyelocytic leukemia HL-60 (lanes 2 and 5) and acute T-cell leukemia Jurkat (lanes 3 and 6) human cell lysates: 1, 3. Anti-CysLTR1 (extracellular) antibody, (1:200). 4, 6. Anti-CysLTR1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CYSLTR1 (3rd extracell. dom.) antibody

Anti-CYSLTR1 / CYSLT1 antibody IHC of human nasal mucosa, allergic rhinitis, eosinophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified GP, Hu, Ms, Rb P
50 µg / €379.00
  OriGene Technologies, Inc.

CYSLTR1 (C-term) antibody

Anti-CYSLTR1 / CYSLT1 antibody IHC of human nasal mucosa, allergic rhinitis, eosinophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Elephant, Gorilla, Hu, Mky, Ms, Por, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

CYSLTR1 antibody

Western blot (WB) analysis of CysLTR1 antibody (Cat.-No.: AP01196PU-N)  in extracts from COLO205 cells. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CYSLTR1 antibody

Western blot (WB) analysis of CysLTR1 antibody (Cat.-No. AP01264PU-N) at 1/500 dilution. Lane 1: Hela whole cell lysate. Lane 2: HEK293T whole cell lysate. Lane 3: Rat brain tissue lysate. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CYSLTR1 (Center) antibody

Western blot analysis of CYSLTR1 Antibody (Center) Cat.-No AP51175PU-N in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the CYSLTR1 antibody detected the CYSLTR1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CYSLTR1 antibody

CYSLTR1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CYSLTR1 antibody

Immunofluorescence analysis of COS7 cells, using CYSLTR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

CYSLTR1 antibody

Immunofluorescence analysis of COS7 cells, using CYSLTR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

CYSLTR1 antibody

Immunofluorescence analysis of HuvEc cells, using CLTR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

CYSLTR1 antibody

Immunofluorescence analysis of HuvEc cells, using CLTR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

CYSLTR1 antibody

Western blot analysis of CYSLTR1 expression in A10 (A); HT29 (B) whole cell lysates. Rabbit Aff - Purified Hu, Mky IP, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CYSLTR1 antibody

Western blot analysis of CYSLTR1 expression in A10 (A); HT29 (B) whole cell lysates. Rabbit Aff - Purified Hu, Mky IP, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CYSLTR1 antibody

Western blot analysis of CYSLTR1 expression in A10 (A); HT29 (B) whole cell lysates. Rabbit Aff - Purified Hu, Mky IP, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CYSLTR1 antibody

Western Blot: CysLTR1 Antibody [NBP1-00776] - Western blot (WB) analysis of CysLTR1 (K172) antibody in extracts from COS-7 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CYSLTR1 antibody

Immunohistochemistry-Paraffin: CYSLTR1 Antibody [NBP1-85356] - Immunohistochemical staining of human lung shows strong cytoplasmic positivity in macrophages. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

CYSLTR1 antibody

Cysteinyl Leukotriene Receptor 1 (CysLT1) detection using NLS 1320 in human nasal mucosa (allergic rhinitis eosinophils). Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CYSLTR1

CYSLTR1 Human
2 µg / €450.00
  Abnova Taiwan Corp.

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