Cystatin-B antibody

Principal name

Cystatin-B antibody

Alternative names for Cystatin-B antibody

Stefin-B, CPI-B, CSTB, CST6, STFB, Liver thiol proteinase inhibitor

SwissProt ID

P01041 (Rat), P04080 (Human), P25417 (Bovin), Q10994 (Sheep), Q29290 (Pig), Q62426 (Mouse)

Gene ID

1476 (CSTB), 13014 (Cstb)

Available reactivities

Hu (Human), Can (Canine), Rt (Rat), Ms (Mouse), Por (Porcine), Rb (Rabbit), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Sh (Sheep)

Available hosts

Mouse, Rabbit, Goat, Rat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Neutralisation (NEUT)

Background of Cystatin-B antibody

CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

General readings

Turk V, et al (1991) FEBS Lett. 285 (2): 213-9. Jarvinen M, et al, (1988) Acta Histochem. 82 (1): 5-18.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cystatin-B antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 M2-F1 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Cystatin-B antibody

Immunoperoxidase of monoclonal antibody to CSTB on formalin-fixed paraffin-embedded human colon tissue. [antibody concentration 5ug/ml] Mouse IgG1 M2-F1 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cystatin-B antibody

(0.1ug/ml) staining of Human Lungs (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-B antibody

Western blot analysis of extracts from A549 cells, using Stefin B antibody (#TA313376).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cystatin-B antibody

CSTB antibody - middle region validated by WB using Transfected 293T cell lysate at 0.25 ug/ml. Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Cystatin-B antibody

WB Suggested Anti-CSTB Antibody Titration: 0.25 ug/ml; Positive Control: 293T cells lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Cystatin-B antibody

Western blot analysis on A549 cell lysate using CSTB Antibody Rabbit IgG Purified Hu, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-B antibody

Western blot analysis of recombinant Human Cystatin B. Mouse IgG1 RJMW2E7 Aff - Purified Hu C, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Cystatin-B (1-98) antibody

The Cell lysates of A549 (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CSTB (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b 2F1 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Cystatin-B (1-98) antibody

The Cell lysates of A549 (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CSTB (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b 2F1 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

Cystatin-B antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 M1-C1 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Cystatin-B antibody

Immunohistochemistry (IHC) analysis of Crystatin-B antibody Cat.-No AP06334PU-N in paraffin-embedded Human breast carcinoma tissue. Rabbit Aff - Purified Hu, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cystatin-B antibody

Cystatin-B Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Cystatin-B antibody

Western Blot analysis of CSTB expression in transfected 293T cell line (H00001476-T01) by CSTB MaxPab polyclonal antibody.

Lane1:CSTB transfected lysate(10.89 KDa).
Lane 2:Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Cystatin-B antibody

CSTB MaxPab polyclonal antibody. Western Blot analysis of CSTB expression in human placenta. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Cystatin-B antibody

CSTB MaxPab rabbit polyclonal antibody. Western Blot analysis of CSTB expression in human placenta. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Cystatin-B antibody

Immunoperoxidase of monoclonal antibody to CSTB on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] Mouse IgG1 M1-C1 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cystatin-B antibody

Cystatin-B Mouse IgG1 S3 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Cystatin-B antibody

Western blot analysis of cell lysate of A - 549 ( 35 ug ) was resolved by SDS - PAGE , transferred to NC membrane and probed with CSTB monoclonal antibody , clone 2F1 ( 1 : 1000 ) ( Cat # MAB1127 ) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b 2F1 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Cystatin-B antibody

Cystatin-B Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

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