Cystatin-C antibody

Principal name

Cystatin-C antibody

Alternative names for Cystatin-C antibody

Cystatin C, Cystatin-3, CST3, Neuroendocrine basic polypeptide, Gamma-trace, Post-gamma-globulin

SwissProt ID

O97862 (Rabit), P01034 (Human), P01035 (Bovin), P14841 (Rat), P21460 (Mouse)

Gene ID

1471 (CST3), 13010 (Cst3), 25307

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Dros (Drosophila), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), ELISA (capture) (E(capture)), Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Luminex (LMNX)

Background of Cystatin-C antibody

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. (provided by RefSeq)Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

General readings

1. Mi W, Pawlik M, Sastre M, Jung SS, Radvinsky DS, Klein AM, Sommer J, Schmidt SD, Nixon RA, Mathews PM, Levy E.
Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models.
Nat. Genet. 2007 Dec 39 (12): 1440-2.
PMID: 18026100

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cystatin-C antibody

  CST3 (Cystatin C) mouse monoclonal antibody, clone OTI2C8 (formerly 2C8)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CST3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504442) Mouse IgG1 OTI2C8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cystatin-C antibody

  Goat Polyclonal Antibody against Cst3  
TA302790 staining (2µg/ml) of mouse kidney lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Goat Anti-CST3 / cystatin C Antibody  
TA305611 (1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Rabbit polyclonal anti-CST3 antibody  
Western blot analysis of extracts from COS-7 cells, using CST3 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Anti-CST3 Rabbit Polyclonal Antibody  
Predicted band size: 16 kDa . Positive control: Human fetal brain tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/2400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal Cystatin C Antibody  
Cystatin-C Mouse IgG1 6F12-C7-D8 Purified
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal Cystatin C Antibody  
Cystatin-C Mouse IgG1 7F6-A5-F3 Purified
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal anti-Cystatin C Antibody  
Cystatin-C Mouse IgG1 E4C6(2A10H7) Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal anti-Cystatin C Antibody  
Cystatin-C Mouse IgG1 E5F6(3C1A12) Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal anti-Cystatin C Antibody  
Cystatin-C Mouse IgG1 E3H9(1D2C10) Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal anti-Cystatin C Antibody  
Cystatin-C Mouse IgG1 M4A9(1F12A10) Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal anti-Cystatin C Antibody  
Cystatin-C Mouse IgG1 M6E3(4B10C9) Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Mouse Monoclonal anti-Cystatin C Antibody  
Cystatin-C Mouse IgG1 E8G1(2A10E7) Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  CST3 (Cystatin C) mouse monoclonal antibody, clone OTI2C11 (formerly 2C11)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CST3 (RC210730, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CST3. Mouse IgG1 OTI2C11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cystatin-C antibody

  CST3 (Cystatin C) mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)  
Immunofluorescent staining of HeLa cells using anti-CST3 mouse monoclonal antibody (TA504494). Mouse IgG1 OTI1A6 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Cystatin-C antibody

  CST3 (Cystatin C) mouse monoclonal antibody, clone OTI7G8 (formerly 7G8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CST3 (RC210730, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CST3. Mouse IgG1 OTI7G8 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cystatin-C antibody

  CST3 (Cystatin C) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CST3 (RC210730, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CST3. Mouse IgG1 OTI7B8 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cystatin-C antibody

  Rabbit Polyclonal Cystatin C Antibody  
ELISA: Cystatin C Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Luminex validated CST3 mouse monoclonal antibody (clone 2C8, clone OTI2C8 (formerly 2C8)  
CST3 Luminex Elisa with 2C8 Capture (TA600251) and Anti-Tag 1B12 Detection (TA700050) Antibodies. Substrate used: Recombinant Human CST3 (TP310730) Mouse IgG1 OTI2C8 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cystatin-C antibody

  Luminex validated CST3 mouse monoclonal antibody (clone 2C1, clone OTI2C11 (formerly 2C11)  
CST3 Luminex Elisa with 2C11 Capture (TA600252) and Anti-Tag 1B12 Detection (TA700050) Antibodies. Substrate used: Recombinant Human CST3 (TP310730) Mouse IgG1 OTI2C11 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

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