Cystatin-D antibody

Principal name

Cystatin-D antibody

Alternative names for Cystatin-D antibody

CST5, Cystatin-5

SwissProt ID

P28325 (Human)

Gene ID

1473 (CST5)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Neutralisation (NEUT), Paraffin Sections (P)

Background of Cystatin-D antibody

The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.

General readings

Balbin M. et al. (1994) J Biol Chem. 269:23156-23162.Alvarez-Fernandez M. et al. (2005) J Biol Chem. 280:18221-18228.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cystatin-D antibody

Western Blot analysis of CST5 expression in transfected 293T cell line (H00001473-T01) by CST5 MaxPab polyclonal antibody.

Lane 1: CST5 transfected lysate(15.62 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cystatin-D

Cystatin-D Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

Cystatin-D (26-142, His-tag)

Cystatin-D Human Purified > 90 % by SDS - PAGE
0.25 mg / €940.00
  Acris Antibodies GmbH

Cystatin-D (26-142, His-tag)

Cystatin-D Human Purified > 90 % by SDS - PAGE
50 µg / €300.00
  Acris Antibodies GmbH

Cystatin-D

Cystatin-D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Cystatin-D

Cystatin-D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CST5 293T Cell Transient Overexpression Lysate(Denatured)

CST5 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

CST5 overexpression lysate

CST5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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