Cytochrome P450 Reductase antibody

Principal name

Cytochrome P450 Reductase antibody

Alternative names for Cytochrome P450 Reductase antibody

CPR, P450R, POR, CYPOR, NADPH--cytochrome P450 reductase

SwissProt ID

P00388 (Rat), P00389 (Rabit), P04175 (Pig), P16435 (Human), P37040 (Mouse), Q3SYT8 (Bovin)

Gene ID

5447 (POR), 29441 (Por), 18984

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Dros (Drosophila), Av (Birds), GP (Guinea Pig), Hst (Hamster), Mky (Monkey), Sh (Sheep), Eq (Equine)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of Cytochrome P450 Reductase antibody

POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this POR gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Fanni D, Nemolato S, Ganga R, Senes G, Gerosa C, Van Eyken P, Geboes K, Faa G, Cytokeratin 20-positive hepatocellular carcinoma. European journal of histochemistry : EJH 53 (4): 269-73.
PMID: 20007098

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cytochrome P450 Reductase antibody

  anti-POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI3H10 (formerly 3H10)  
Immunohistochemical staining of paraffin-embedded endometrium tissue within the normal limits using anti-PORmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500572, Dilution 1:50) Mouse IgG1 OTI3H10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI5H5 (formerly 5H5)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500579) Mouse IgG1 OTI5H5 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI4G2 (formerly 4G2)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500591) Mouse IgG1 OTI4G2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500600) Mouse IgG1 OTI2E4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI6C4 (formerly 6C4)  
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500601) Mouse IgG1 OTI6C4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI1B11 (formerly 1B11)  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500611) Mouse IgG1 OTI1B11 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI5B3 (formerly 5B3)  
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500612) Mouse IgG2a OTI5B3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  anti-POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI5B6 (formerly 5B6)  
Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-PORmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500613, Dilution 1:50) Mouse IgG1 OTI5B6 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

  POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI3F10 (formerly 3F10)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-POR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500633) Mouse IgG2a OTI3F10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Cytochrome P450 Reductase antibody

AP21520PU-N CYPOR antibody staining of Rat Liver lysate at 0.1 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cytochrome P450 Reductase antibody

  Rabbit Polyclonal Anti-POR Antibody  
WB Suggested Antibody Titration: 2.5 ug/ml; Positive Control: 293T Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cytochrome P450 Reductase antibody

  Rabbit Polyclonal Anti-POR Antibody  
WB Suggested Anti-POR Antibody Titration: 0.25 ug/ml; Positive Control: 293T cells lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

POR - human gene knockout kit via CRISPR

POR - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

POR - human gene knockout kit via CRISPR

POR - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

POR - human gene knockout kit via CRISPR

POR - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cytochrome P450 Reductase

  Recombinant protein of human P450 (cytochrome) oxidoreductase (POR)  
Cytochrome P450 Reductase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Cytochrome P450 Reductase (1-680, His-tag)

Cytochrome P450 Reductase Human Purified > 85 % by SDS – PAGE.
0.25 mg / €730.00
  Acris Antibodies GmbH

Cytochrome P450 Reductase (1-680, His-tag)

Cytochrome P450 Reductase Human Purified > 85 % by SDS – PAGE.
50 µg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

POR overexpression lysate

POR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

POR-knockout Cell lysate

POR-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Items 1 to 20 of 26 total

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