Cytoglobin antibody

Principal name

Cytoglobin antibody

Alternative names for Cytoglobin antibody

Histoglobin, CYGB, STAP, HGb, Stellate cell activation-associated protein

SwissProt ID

Q8WWM9 (Human), Q921A4 (Rat), Q9CX80 (Mouse)

Gene ID

114757 (CYGB), 114886 (Cygb), 170520

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Cytoglobin antibody

Cytoglobin(CYGB),also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir by Sawai et al.

General readings

Hankeln T., et al. (2002) Mol Biol Evol. 19(4):416-21.
Gazdar AF., et al. (2008) Cancer Res. 68(18):7448-56.

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cytoglobin (N-term) antibody

Western blot analysis of Cytoglobin (N-term) Cat.-No AP51162PU-N in HepG2 cell line lysates (35ug/lane). This demonstrates the CYGB antibody detected the CYGB protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CYGB - human gene knockout kit via CRISPR

CYGB - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CYGB - human gene knockout kit via CRISPR

CYGB - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYGB - human gene knockout kit via CRISPR

CYGB - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYGB - human gene knockout kit via CRISPR

CYGB - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cygb - mouse gene knockout kit via CRISPR

Cygb - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cygb - mouse gene knockout kit via CRISPR

Cygb - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cygb - mouse gene knockout kit via CRISPR

Cygb - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cygb - mouse gene knockout kit via CRISPR

Cygb - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cytoglobin

  Recombinant protein of human cytoglobin (CYGB)  
Cytoglobin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Cytoglobin (1-190, His-tag)

Cytoglobin Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

Cytoglobin (1-190, His-tag)

Cytoglobin Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

CYGB overexpression lysate

CYGB overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CYGB (mGFP-tagged) - Human cytoglobin (CYGB), 200 uL, >10^7 TU/mL

Lenti ORF particles, CYGB (mGFP-tagged) - Human cytoglobin (CYGB), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, CYGB (Myc-DDK tagged) - Human cytoglobin (CYGB) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CYGB (Myc-DDK tagged) - Human cytoglobin (CYGB) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cygb (GFP-tagged ORF) - Rat cytoglobin (Cygb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cygb (GFP-tagged ORF) - Rat cytoglobin (Cygb), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cygb (Myc-DDK-tagged ORF) - Rat cytoglobin (Cygb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cygb (Myc-DDK-tagged ORF) - Rat cytoglobin (Cygb), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

per page
  • LinkedIn