Cytokeratin 1 antibody

Principal name

Cytokeratin 1 antibody

Alternative names for Cytokeratin 1 antibody

Keratin-1, KRT1, K1, Cytokeratin 1, Hair alpha protein, 67 kDA cytokeratin, KRTA, Keratin type II cytoskeletal 1

SwissProt ID

P04104 (Mouse), P04264 (Human), Q6EIY9 (Canfa), Q6IMF3 (Rat)

Gene ID

3848 (KRT1), 16678 (Krt1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Mky (Monkey), Rb (Rabbit), Rt (Rat), Can (Canine), Chk (Chicken), Por (Porcine)

Available hosts

Guinea Pig, Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Cytokeratin 1 antibody

Cytokeratins, a group of at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 4, 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Cytokeratin peptide 4 (59 kDa) is the secondary type II keratin expressed in non cornified stratified squamous epithelia. Cytokeratin peptide 5 (58 kDa) is the primary type II keratin in stratified epithelia, while cytokeratin type 8 (52 kDa) is a major type II keratin in simple epithelia. Cytokeratin 6 (56 kDa) is a \hyperproliferation\" cytokeratin expressed in tissues with natural or pathological high turnover. Cytokeratins 10, 13 and 18 are members of the type I acidic subfamily. Cytokeratin peptide 10 (56 kDa) is the secondary type I keratin expressed in cornified epithelia. Cytokeratin 13 (54 kDa) is the secondary type I keratin expressed in non-cornified stratified squamous epithelia. Cytokeratin 18 (45 kDa) is the primary type I keratin expressed in simple epithelial cells.Cytokeratin is a heterotetramer of two type I and two type II keratins. Keratin 1 is generally associated with keratin 10. Defects in Cytokeratin are a cause of epidermolytic hyperkeratosis, also known as bullous congenital ichthyosiform erythroderma (BIE), which is a hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. Defects in Cytokeratin are also the cause of Curth Macklin type ichthyosis hystrix, nonepidermolytic palmoplantar keratoderma, annular epidermolytic ichthyosis and keratosis palmoplantaris striata III (PPKS3). PPKS3 is an autosomal dominant disorder affecting palm and sole skin where stratum corneum and epidermal layers are thickened. There is no involvement of nonpalmoplantar skin, and both hair and nails are normal."""

General readings

This product has been used in:Machesney M et al. Activated keratinocytes in the epidermis of hypertrophic scars. Am J Pathol 152:1133-41 (1998). PubMed PMID: 9588880

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cytokeratin 1 antibody

Immunohistochemistry: AM20162SU-N KRT1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Liver tissue, colon carcinoma, lung carcinoma, and esophagus tissue using DAB staining. Mouse IgG1 3C10F7, 3C10G5, PMC01, 4D12B3 Ascites Hu C, E, P, WB
0.1 ml / €410.00
  Acris Antibodies GmbH

Cytokeratin 1 antibody

Western Blot: Cytokeratin 1 Antibody (LHK1) - Western blot analysis of Cytokeratin 1 in Caco-2 using anti-LHK1. Mouse IgG2a LHK1 Purified Hu C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cytokeratin 1 (Center) antibody

KRT1 Antibody (Center) (Cat. #AP52410PU-N) IHC analysis in formalin fixed and paraffin embedded skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KRT1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Purified E, Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Cytokeratin 1 antibody

Cytokeratin 1 Guinea Pig Serum Hu, Ms C, ICC/IF, P, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

Cytokeratin 1 antibody

KRT1 polyclonal antibody (A01), Lot # 051122JC01 Western Blot analysis of KRT1 expression in MES-SA/Dx5 ( Cat # L021V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Cytokeratin 1 antibody

Cytokeratin 1 Mouse IgG2a 2A7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cytokeratin 1 antibody

Human Skin; Rabbit Anti-KRT1 Antibody. Catalog Number: arp42278. Paraffin Embedded Tissue: Human Skin. Antibody Concentration: 1.25-2.5 ug/ml; KRT1 antibody - middle region (ARP42278_P050) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

Cytokeratin 1 antibody

Cytokeratin AE1 Antibody [CK 210 (AE1)] Mouse IgG1 AE1 Purified Bov, Chk, Hu, Mky, Ms, Por, Rb, Rt C, ICC/IF, P
0.2 ml / €400.00
  Immuquest

Cytokeratin 1 antibody

Cytokeratin 1 Mouse IgG2a LHK1 Hu C, ICC/IF, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

Cytokeratin 1 antibody

Western Blot: CK1 Antibody (PMC01) [NB110-89450] - truncated CK1 recombinant protein. Mouse PMC01 Ascites Hu C, E, P, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cytokeratin 1

Cytokeratin 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Cytokeratin 1

Cytokeratin 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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