Cytokeratin 10 antibody

Principal name

Cytokeratin 10 antibody

Alternative names for Cytokeratin 10 antibody

Cytokeratin-10, CK10, CK-10, Keratin-10, KRT10, KPP, K10, Keratin, Type I Cytoskeletal 10

SwissProt ID

P02535 (Mouse), P06394 (Bovin), P13645 (Human), Q6EIZ0 (Canfa), Q6IFW6 (Rat)

Gene ID

3858 (KRT10), 3860 (KRT13), 938586 (alkA)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Fe (Feline), Bov (Bovine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Guinea Pig

Available applications

Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of Cytokeratin 10 antibody

Cytokeratin 10 is a heterotetramer of two type I and two type II keratins. Cytokeratin 10 is generally associated with keratin 1. It is seen in all suprabasal cell layers including stratum corneum. A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560). Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq. EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. At birth, affected individuals usually present with redness, blisters and superficial erosions due to cytolysis. Within a few weeks, the erythroderma and blister formation diminish and hyperkeratoses develop. Transmission is autosomal dominant, but most cases are sporadic. Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens.

General readings

1. Butovich IA  et al. Biophysical and morphological evaluation of human normal and dry eye meibum using hot stage polarized light microscopy. Invest Ophthalmol Vis Sci 55:87-101 (2014). PubMed: 24282231
2. Kawabata K  et al. The presence of N(e)-(Carboxymethyl) lysine in the human epidermis. Biochim Biophys Acta 1814:1246-52 (2011). WB, IHC-P ; Human . PubMed: 21708295

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 DE-K10 Supernatant Can, Fe, Hu C, P, WB
1 ml / €340.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Figure 3. Immunohistochemistry on paraffin section of human skin. Mouse IgG1 RKSE60 Purified Can, Hu, Ms, Por, Rt, Ze C, F, ICC/IF, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 SPM261 Purified Hu, Ms C, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 SPM261 Purified Hu, Ms C, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 SPM261 Purified Hu, Ms C, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 LH2 Purified Hu, Ms C, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 LH2 Purified Hu, Ms C, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Cytokeratin 10 Mouse IgG1 LH2 Purified Hu, Ms C, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

AP23795PU Cytokeratin-10 antibody staining of Human Skin. Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

AP23795PU Cytokeratin-10 antibody staining of Human Skin. Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

AP23795PU Cytokeratin-10 antibody staining of Human Skin. Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA308915 diluted at 1:500. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cytokeratin 10 antibody

Western blot analysis of extracts from HeLa cells, using Keratin 10 antibody (#TA314141).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cytokeratin 10 antibody

Predicted cell location: Cytoplasm, Cell membrane . Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using KRT10 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cytokeratin 10 antibody

Predicted band size: 59 kDa. Positive control: MCF7 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cytokeratin 10 antibody

Predicted band size: 59 kDa. Positive control: MCF7 cell lysate. Recommended dilution: 1/1000-5000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/750 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cytokeratin 10 antibody

Western blot analysis on HeLa cell lysate using Keratin 10 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cytokeratin 10 (+KRT13) antibody

Cytokeratin 10 Mouse IgG2a CK208 Purified Hu C, ICC/IF
1 ml / €360.00
  Acris Antibodies GmbH

Cytokeratin 10 (+KRT13) antibody

Cytokeratin 10 Mouse IgG2a CK208 Purified Hu C, ICC/IF
0.5 ml / €270.00
  Acris Antibodies GmbH

Cytokeratin 10 antibody

Western blot (WB) analysis of Cytokeratin 10 antibody (Cat.-No.: AP06194PU-N) at 1/500 dilution:Lane1: HeLa whole cell lysateLane2: Raw264.7 whole cell lysateLane3: NIH-3T3 whole cell lysateLane4: Rat brain tissue lysate Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

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