Cytokeratin 13 antibody

Principal name

Cytokeratin 13 antibody

Alternative names for Cytokeratin 13 antibody

CK-13, CK13, Keratin-13, KRT13, K13, KRT-13, Keratin type I cytoskeletal 13

SwissProt ID

P08730 (Mouse), P13646 (Human), P13646-3, Q6IFV4 (Rat)

Gene ID

3860 (KRT13), 16663 (Krt13), 287699

Available reactivities

Fe (Feline), Hu (Human), Rt (Rat), Ze (Zebrafish), Can (Canine), Bov (Bovine), Ms (Mouse), Chk (Chicken), African clawed frog, Mky (Monkey), Prim (Primate), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Guinea Pig, Rabbit, Goat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of Cytokeratin 13 antibody

KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia.The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.

General readings

Matta H, Mazzacurati L, Schamus S, Yang T, Sun Q, Chaudhary PM.
Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NFkappaB without JNK activation.
J Biol Chem. 2007 Aug 24;282(34):24858-65.

2 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cytokeratin 13 antibody

  Rabbit Polyclonal Anti-KRT13 Antibody  
WB Suggested Anti-KRT13 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: NCI-H226 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

Cytokeratin 13 antibody

  Rabbit Polyclonal Anti-KRT13 Antibody  
WB Suggested Anti-KRT13 Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

2 Item(s)

per page
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