D8-D7 sterol isomerase antibody

Principal name

D8-D7 sterol isomerase antibody

Alternative names for D8-D7 sterol isomerase antibody

EBP, CPX, CHO2, CPXD, CDPX2, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, Cholestenol Delta-isomerase, Delta(8)-Delta(7) sterol isomerase, Emopamil-binding protein

SwissProt ID

Q15125 (Human)

Gene ID

10682 (EBP)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of D8-D7 sterol isomerase antibody

EBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in EBP gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).Emopamil-binding protein (EBP) is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. EBP shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of EBP is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).

General readings

Berthois,Y., (2003) Br. J. Cancer 88 (3), 438-446

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

D8-D7 sterol isomerase antibody

WB Suggested Anti-EBP Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate.EBP is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

D8-D7 sterol isomerase antibody

Human Jurkat; WB Suggested Anti-EBP Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate. EBP is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; EBP antibody - N-terminal region (ARP46742_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

D8-D7 sterol isomerase antibody

Western Blot: EBP Antibody [NBP1-59782] - This Anti-EBP antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

D8-D7 sterol isomerase antibody

Immunohistochemistry-Paraffin: EBP Antibody [NBP1-85699] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in Leydig cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

D8-D7 sterol isomerase

D8-D7 sterol isomerase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

5 Item(s)

per page
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