DACT2 antibody

Principal name

DACT2 antibody

Alternative names for DACT2 antibody

dapper homolog 2, DAPPER2, PP13671, DPR2, C6orf116

SwissProt ID

Q5SW24 (Human), Q7TN08 (Mouse)

Gene ID

168002 (DACT2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of DACT2 antibody

The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact2 is most prominent during the development of the thymus kidneys, and salivary gland. Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling. Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors. At least two isoforms of Dact2 are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DACT2 antibody

Western blot analysis of Dact2 in SK-N-SH cell lysate with Dact2 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DACT2 (N-term) antibody

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

DACT2 Control Peptide

DACT2
50 µg / €160.00
  Acris Antibodies GmbH

DACT2 antibody

DACT2 Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

DACT2 antibody

Immunohistochemistry-Paraffin: Dact2 Antibody [NBP1-76955] - Human brain tissue with Dact2 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

DACT2 antibody

Immunohistochemistry-Paraffin: Dact2 Antibody [NBP1-88755] Immunohistochemical staining of human liver shows strong granular cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

DACT2 antibody

Immunohistochemistry-Paraffin: Dact2 Antibody [NBP1-88756] Immunohistochemical staining of human prostate shows strong granular positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DACT2

DACT2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DACT2

DACT2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DACT2 overexpression lysate

DACT2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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