DAP10 / HCST antibody

Principal name

DAP10 / HCST antibody

Alternative names for DAP10 / HCST antibody

Hematopoietic cell signal transducer, KAP10, PIK3AP, Transmembrane adapter protein KAP10, DNAX-activation protein 10, Membrane protein DAP10

SwissProt ID

Q1XF11 (Bovin), Q6X9T8 (Rat), Q9GJR5 (Pig), Q9QUJ0 (Mouse), Q9UBK5 (Human)

Gene ID

10870 (HCST)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of DAP10 / HCST antibody

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Upshaw JL, Arneson LN, Schoon RA, Dick CJ, Billadeau DD, Leibson PJ. NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. Nat Immunol. 2006 May;7(5):524-32. Epub 2006 Apr 2.
PMID: 16582911

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DAP10 / HCST (C-term) antibody

TA303159 (0.2µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DAP10 / HCST antibody

HCST polyclonal antibody ( Cat # PAB7141 ) ( 0.2 µg/ml ) staining of human spleen lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

DAP10 / HCST antibody

Western Blot: HCST Antibody [NB100-55403] - NB100-55403 (0.2ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DAP10 / HCST (transcript variant 2)

DAP10 / HCST Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HCST overexpression lysate

HCST overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HCST overexpression lysate

HCST overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

6 Item(s)

per page
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