DAPK2 / DRP-1 antibody

Principal name

DAPK2 / DRP-1 antibody

Alternative names for DAPK2 / DRP-1 antibody

DAP kinase 2, Death-associated protein kinase 2, DAP-kinase-related protein 1

SwissProt ID

Q8VDF3 (Mouse), Q9UIK4 (Human)

Gene ID

23604 (DAPK2), 9262 (STK17B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of DAPK2 / DRP-1 antibody

DAP (death associated protein) kinase and ZIP kinase are members of a novel protein kinase family, the members of which have the capacity to mediate apoptosis through their catalytic activities. DAP kinase contains a “death domain” and has been shown to mediate gamma interferon-induced apoptosis. The introduction of DAP kinase into highly metastatic carcinoma clones lacking DAP kinase expression was shown to result in the suppression of metastasis, thus linking suppression of apoptosis to metastasis. ZIP kinase contains a leucine zipper domain, which is necessary for homodimerization and for interaction with other leucine zipper proteins. ZIP kinase dimerizes with ATF-4, an ATF/CREB transcription factor family member that contains a leucine zipper. Overexpression of ZIP kinase was shown to result in morphological changes associated with apoptosis in NIH/3T3 cells.

General readings

1、Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ, Jenkins NA, Akira S (Jun 1999). "Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity". Oncogene 18 (23): 3471–80.
2、"Entrez Gene: DAPK2 death-associated protein kinase 2".
3、"New Modularity of DAP-Kinases: Alternative Splicing of the DRP-1 Gene Produces a ZIPk-Like Isoform".

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DAPK2 / DRP-1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-DAPK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501086) Mouse IgG1 OTI1F7 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

DAPK2 / DRP-1 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-DAPK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501087) Mouse IgG3 OTI1C8 Purified Hu F, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

DAPK2 / DRP-1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-DAPK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501088) Mouse IgG2b OTI1B5 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

DAPK2 / DRP-1 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-DAPK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501099) Mouse IgG3 OTI1C5 Purified Can, Hu, Mky, Rt F, ICC/IF, IP, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

DAPK2 / DRP-1 antibody

Anti-DAPK2 mouse monoclonal antibody (TA501204) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2(RC216274). Mouse IgG2b OTI1B10 Purified Hu F, ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

DAPK2 / DRP-1 antibody

Human breast ca stained with Anti-DRAK2 Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 antibody

Human breast ca stained with Anti-DRAK2 Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 antibody

Human breast ca stained with Anti-DRAK2 Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 (C-term) antibody

TA302461 staining (2µg/ml) of mouse brain extracts (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DAPK2 / DRP-1 antibody

Western blot analysis of DAPK2 in A431 (H), mouse spleen (M), and rat kidney (R) lysates with DAPK2 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DAPK2 / DRP-1 antibody

Figure 2. Formalin-Fixed Paraffin-Embedded (FFPE) on Prostate. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 (N-term) antibody

Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with DAPK2 Antibody (N-term) (AP13896PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 antibody

Immunohistochemistry analyzes of DAPK2 antibody (AP20220PU-N) in paraffin-embedded human skeletal muscle tissue. Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €350.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 (C-term) antibody

Human Breast (formalin-fixed, paraffin-embedded) stained with DAPK2 antibody AP22565PU-N followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Platypus, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 Control Peptide

DAPK2 / DRP-1
50 µg / €160.00
  Acris Antibodies GmbH

DAPK2 / DRP-1 antibody

DAPK2 monoclonal antibody (M01), clone 3D4 Western Blot analysis of DAPK2 expression in A-431 ( Cat # L015V1 ). Mouse IgG1 3D4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DAPK2 / DRP-1 antibody

DAPK2 / DRP-1 Mouse IgG1 1A2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

DAPK2 / DRP-1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with DAPK2 polyclonal antibody ( Cat # PAB2780 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

DAPK2 / DRP-1 antibody

DAPK2 polyclonal antibody ( Cat # PAB6091 ) staining ( 2 µg/ml ) of mouse brain extracts ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

DAPK2 / DRP-1 antibody

Immunohistochemical staining of DAPK2 on formalin fixed, paraffin embedded human breast ca with DAPK2 polyclonal antibody. Rabbit Hu P
0.1 ml / €390.00
  Abnova Taiwan Corp.

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