DBF4 / ASK antibody
Principal name
DBF4 / ASK antibody
Alternative names for DBF4 / ASK antibody
DBF4A, ZDBF1, Chiffon homolog A, Protein DBF4 homolog A, Activator of S phase kinase, DBF4-type zinc finger-containing protein 1
Ncbi ID
9606, NP_006707, NP_006707.1, NP_001177646, AAH36045, NM_006716, NP_001177646.1
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of DBF4 / ASK antibody
The Dbf4/Cdc7 protein kinase is essential for the activation of replication origins during S phase. Cdc7-Dbf4 efficiently phosphorylates several proteins that are required for the initiation of DNA replication, including five of the six minichromosome maintenance (Mcm) proteins and the p180 subunit of DNA polymerase alpha-primase. This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4, and the kinase activity of the complex is regulated throughout the cell cycle mainly by fluctuating levels of Dbf4. Cdc7 is consistently expressed throughout the cell cycle, while the expression of Dbf4 is absent during G1 phase and accumulates during S and G2 phases. The anaphase-promoting complex rapidly degrades Dbf4 at the time of chromosome segregation, and the stability of Dbf4 remains low during pre-Start G1 phase. The coordinated degradation of Dbf4 and the time of chromosome separation is important to ensuring that prereplicative complexes, which assemble after chromosome segregation, do not immediately refire.















Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA311409 | DBF4 / ASK antibody |
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Goat Anti-Dbf4 (mouse) Antibody | |||||||
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Goat | Aff - Purified | Ms, Rt | E, WB |
0.1 mg /
€360.00
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OriGene Technologies, Inc. | |||||||
TA315124 | DBF4 / ASK antibody |
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Rabbit polyclonal anti-DBF4 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
AP20463PU-N | DBF4 / ASK antibody |
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Rabbit | Aff - Purified | Hu, Ms | P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
C11821-1 | DBF4 / ASK antibody |
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Rabbit | Aff - Purified | Hu, Ms | E, WB |
50 µg /
€230.00
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Assay Biotech | |||||||
C11821-2 | DBF4 / ASK antibody |
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Rabbit | Aff - Purified | Hu, Ms | E, WB |
0.1 mg /
€330.00
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Assay Biotech |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN206120 | DBF4 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206120BN | DBF4 - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206120LP | DBF4 - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206120RB | DBF4 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN304287 | Dbf4 - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304287BN | Dbf4 - mouse gene knockout kit via CRISPR |
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304287LP | Dbf4 - mouse gene knockout kit via CRISPR |
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304287RB | Dbf4 - mouse gene knockout kit via CRISPR |
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Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Lysates
Catalog No. | ||
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LY402007 | DBF4 overexpression lysate |
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0.1 mg /
€295.00
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|
OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
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RC206120L2V | Lenti ORF particles, DBF4 (mGFP-tagged) - Human DBF4 homolog (S. cerevisiae) (DBF4), 200 uL, >10^7 TU/mL |
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200 µl /
€1,082.00
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OriGene Technologies, Inc. | ||
RC206120L1V | Lenti ORF particles, DBF4 (Myc-DDK tagged) - Human DBF4 homolog (S. cerevisiae) (DBF4) , 200 uL, >10^7 TU/mL |
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200 µl /
€969.00
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OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
Catalog No. | ||
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MR222369L2V | Lenti ORF particles, Dbf4 (GFP-tagged) - Mouse DBF4 homolog (S. cerevisiae) (Dbf4), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€1,381.00
|
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OriGene Technologies, Inc. | ||
MR222368L2V | Lenti ORF particles, Dbf4 (GFP-tagged) - Mouse DBF4 homolog (S. cerevisiae) (Dbf4), transcript variant 2, 200 uL, >10^7 TU/mL |
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200 µl /
€1,381.00
|
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OriGene Technologies, Inc. | ||
MR222369L1V | Lenti ORF particles, Dbf4 (Myc-DDK-tagged) - Mouse DBF4 homolog (S. cerevisiae) (Dbf4), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€1,236.00
|
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OriGene Technologies, Inc. | ||
MR222368L1V | Lenti ORF particles, Dbf4 (Myc-DDK-tagged) - Mouse DBF4 homolog (S. cerevisiae) (Dbf4), transcript variant 2, 200 uL, >10^7 TU/mL |
|
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200 µl /
€1,236.00
|
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OriGene Technologies, Inc. | ||