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DBI / ACBP antibody

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Principal name

DBI / ACBP antibody

Alternative names for DBI / ACBP antibody

Diazepam-binding inhibitor, Endozepine, Acyl-CoA-binding protein

SwissProt ID

P07107 (Bovin), P07108 (Human), P11030 (Rat), P31786 (Mouse)

Gene ID

1622 (DBI), 13167 (Dbi), 25045

Ncbi ID

NP_001073331, 9606, NP_065438, NP_001073331.1, NM_001037999, NM_001079862, NM_001079863, NM_001178043, NM_001178017, NM_031853, NM_001178042

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Can (Canine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P)

Background of DBI / ACBP antibody

DBI is diazepam binding inhibitor. The protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate sigl transduction at type A gamma-aminobutyric acid receptors located in brain sypses. DBI is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrel steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate sigl transduction at type A gamma-aminobutyric acid receptors located in brain sypses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrel steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

General readings

Folli F., et al. (2010) PLoS One. 5(3):e9923.
Manjithaya R., et al. (2010) J Cell Biol. 188(4):537-46.

AR09477PU-L - DBI / ACBP
AR09477PU-L - DBI / ACBP
Recombinant human ACBP, 1-87 aa, His-tagged: 15% SDS-PAGE (3 ug)
ARP33135_P050 - DBI / ACBP
Human Brain; Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5ug/ml using anti-DBI antibody (ARP33135_P050); DBI antibody - N-terminal region (ARP33135_P050) in Human Brain cells using Immunohistochemistry
ARP33135_P050 - DBI / ACBP
Human Liver; WB Suggested Anti-DBI Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Liver; DBI antibody - N-terminal region (ARP33135_P050) in Human Liver cells using Western Blot
H00001622-A01 - DBI / ACBP
DBI polyclonal antibody (A01), Lot # 060613JCS1 Western Blot analysis of DBI expression in SJCRH30 ( Cat # L027V1 ).
H00001622-D01P - DBI / ACBP
Western Blot analysis of DBI expression in transfected 293T cell line (H00001622-T02) by DBI MaxPab polyclonal antibody.Lane 1: DBI transfected lysate(11.80 KDa).Lane 2: Non-transfected lysate.
MAB0720 - DBI / ACBP
Immunoprecipitation analysis of HepG2 cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with DBI monoclonal antibody, clone 20B10 ( Cat # MAB0720 ).
MAB0725 - DBI / ACBP
Immunoblot analysis of HepG2 cell lysate.
PAB1215 - DBI / ACBP
Immunoblot analysis of U87 MG cell lysate.
TP308982 - DBI / ACBP
TA332222 - DBI / ACBP
WB Suggested Anti-DBI Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Liver
TA332222 - DBI / ACBP
Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5ug/ml using anti-DBI antibody
TA332648 - DBI / ACBP
Western blot analysis of extracts of various cell lines, using DBI antibody.
TA332648 - DBI / ACBP
Immunofluorescence analysis of MCF-7 cell using DBI antibody. Blue: DAPI for nuclear staining.

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DBI / ACBP antibody
  Rabbit Polyclonal Anti-DBI Antibody  
WB Suggested Anti-DBI Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.
+1 additional image

DBI / ACBP antibody
  Rabbit anti-DBI Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using DBI antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.
+1 additional image

CRISPR

Catalog No. Species Donor Vector  

DBI - human gene knockout kit via CRISPR
DBI - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DBI - human gene knockout kit via CRISPR
DBI - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DBI / ACBP (transcript variant 1)
  Recombinant protein of human diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (DBI), transcript variant 1  
DBI / ACBP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DBI / ACBP (1-87, His-tag)
DBI / ACBP Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €670.00
  Acris Antibodies GmbH
+1 additional image

DBI / ACBP (1-87, His-tag)
DBI / ACBP Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €250.00
  Acris Antibodies GmbH
+1 additional image

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 4, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 6, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 7, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (mGFP-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 7, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 4, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 6, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 7, 200 uL, >10^7 TU/mL
Lenti ORF particles, DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 7, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.
 

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dbi (GFP-tagged) - Mouse diazepam binding inhibitor (Dbi), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Dbi (GFP-tagged) - Mouse diazepam binding inhibitor (Dbi), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Dbi (Myc-DDK-tagged) - Mouse diazepam binding inhibitor (Dbi), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Dbi (Myc-DDK-tagged) - Mouse diazepam binding inhibitor (Dbi), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dbi (GFP-tagged ORF) - Rat diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (Dbi), 200 uL, >10^7 TU/mL
Lenti ORF particles, Dbi (GFP-tagged ORF) - Rat diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (Dbi), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Dbi (Myc-DDK-tagged ORF) - Rat diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (Dbi), 200 uL, >10^7 TU/mL
Lenti ORF particles, Dbi (Myc-DDK-tagged ORF) - Rat diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (Dbi), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.
 

20 Item(s)

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Available Filters

Product Type
  1. CRISPR (2)
  2. Human Lenti ORF Particle (9)
  3. Mouse Lenti ORF Particle (2)
  4. Primary Antibody (2)
  5. Protein | Growth Factor (3)
  6. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (2)
Target
  1. DBI / ACBP (5)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (2)
  3. Rat (Rt) (2)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
  6. Guinea Pig (GP) (1)
  7. Rabbit (Rb) (1)
Applications
  1. Paraffin Sections (P) (1)
  2. Western blot / Immunoblot (WB) (1)
Presentation
  1. Purified (4)
Host
  1. Rabbit (2)
Images
  1. 1 image (5)
Images: Applications
  1. SDS-PAGE (2)
  2. Western blot / Immunoblot (WB) (2)
  3. Immunofluorescence (IF) (1)
  4. IHC (1)
Species (Protein)
  1. Human (3)
Source
  1. E. coli (2)
  2. HEK293 cells (1)
Species (CRISPR)
  1. Human (2)
Donor Vector
  1. GFP-Puro (1)
  2. mBFP-Neo (1)
Manufacturer
  1. Acris - OriGene (20)
Service
  • OriGene EU
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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