DCLRE1A antibody

Principal name

DCLRE1A antibody

Alternative names for DCLRE1A antibody

DNA cross-link repair 1A protein, SNM1, SNM1A, KIAA0086

SwissProt ID

Q5QJC4 (Chick), Q6PJP8 (Human), Q9JIC3 (Mouse)

Gene ID

9937 (DCLRE1A)

Available reactivities

Hu (Human)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of DCLRE1A antibody

SNM1 is a gene that encodes a DNA-crosslink repair protein. SNM1 is the human homolog of a gene first identified in Drosphilia melanogaster and Saccharomyces cerevisiae. SNM1 mutants of Saccharomyces cerevisiae have been shown to be specifically sensitive to DNA interstrand crosslinking agents but not sensitive to monofunctional alkylating agents, UV, or ionizing radiation. To date, 5 homologs of Snm1 have been identified in the mammalian genome and are termed SNM1, SNM1B, Artemis, ELAC2, and CPSF73. Human SNM1 localizes to the cell nucleus in three distinct patterns: diffuse nuclear staining, multiple nuclear foci, or one or two larger bodies confined to the nucleus. Research suggests a function for human Snm1 in the cellular response to double-strand breaks formed by ionizing radiation and interstrand crosslinking agents.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DCLRE1A antibody

DCLRE1A Goat IgG Purified Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

DCLRE1A antibody

DCLRE1A Goat IgG Purified Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

DCLRE1A antibody

Immunohistochemistry-Paraffin: SNM1 Antibody [NBP1-89663] - Immunohistochemical staining of human placenta shows strong nuclear positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

3 Item(s)

per page
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