DCP2 antibody

Principal name

DCP2 antibody

Alternative names for DCP2 antibody

mRNA-decapping enzyme 2, hDpc, NUDT20, Nudix motif 20, Nucleoside diphosphate-linked moiety X motif 20

SwissProt ID

P53550 (Yeast), Q8IU60 (Human), Q9CYC6 (Mouse)

Gene ID

167227 (DCP2)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Paraffin Sections (P), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of DCP2 antibody

DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5\'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277

General readings

Dunckley T and Parker R. The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J. 18:5411-22.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DCP2 antibody

Western blot analysis of Jurkat cell lysates with anti-Dcp2 antibody (1:200). Rabbit Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DCP2 (C-term) antibody

Western blot analysis of DCP2 in 293 cell lysate with DCP2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DCP2 antibody

WB Suggested Anti-DCP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DCP2 antibody

WB Suggested Anti-DCP2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate; DCP2 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DCP2 (Center) antibody

Formalin fixed and paraffin embedded human kidney tissue stained with DCP2 Antibody (Center) Cat.-No AP51202PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DCP2 (C-term) Control Peptide

Western blot analysis of DCP2 in 293 cell lysate with DCP2 antibody Cat.-No. AP55470PU-N at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide Cat.-No. AP55470CP-N.
50 µg / €160.00
  Acris Antibodies GmbH

DCP2 antibody

Immunofluorescence of purified MaxPab antibody to DCP2 on HepG2 cell. [antibody concentration 20 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

DCP2 antibody

Human Placenta; WB Suggested Anti-DCP2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Placenta; DCP2 antibody - middle region (ARP41149_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

DCP2 antibody

Human Jurkat; WB Suggested Anti-DCP2 Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate. DCP2 is supported by BioGPS gene expression data to be expressed in Jurkat.; DCP2 antibody - C-terminal region (ARP41150_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

DCP2 antibody

Western Blot: DCP2 Antibody [NBP1-41070]-Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from 293T cells. Affinity purified rabbit anti-Dcp2 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 10 mcg/mg lysate.  Dcp2 was also immunoprecipitated by another rabbit anti-Dcp2 antibody, which recognizes an upstream epitope. Rabbit Hu IP, PLA, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

DCP2 antibody

Western Blot: DCP2 Antibody [NBP1-57441] - This Anti-DCP2 antibody was used in Western Blot of Placenta tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

DCP2 antibody

Western Blot: DCP2 Antibody [NBP1-57442] - This Anti-DCP2 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DCP2

DCP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DCP2

DCP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DCP2 293T Cell Transient Overexpression Lysate(Denatured)

DCP2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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