DCPS antibody

Principal name

DCPS antibody

Alternative names for DCPS antibody

Scavenger mRNA-decapping enzyme DcpS, DCS1, DCS-1, HINT5, HINT-5, HSL1, HSPC015, Hint-related 7meGMP-directed hydrolase, Histidine triad protein member 5

SwissProt ID

Q8K4F7 (Rat), Q8MIZ3 (Pig), Q8MJJ7 (Bovin), Q96C86 (Human), Q9DAR7 (Mouse)

Gene ID

28960 (DCPS), 5828960 (atpA)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of DCPS antibody

Eukaryotic cells primarily utilize exoribonucleases and decapping enzymes to degrade their mRNA. DcpS is a scavenger pyrophosphatase that hydrolyzes the residual cap structure following 3' to 5' decay of an mRNA. Following mRNA degradation DcpS releases N-7 methyl guanosine monophosphate and 5'-diphosphate terminated cap or mRNA products. The central histidine within the DcpS HIT motif is critical for decapping activity and defines the HIT motif as a new mRNA decapping domain, making DcpS the first member of the HIT family of proteins with a defined biological function. HIT proteins are homodimeric and contain two conserved 100-amino-acid HIT fold domains with independent active sites that are each sufficient to bind and hydrolyze cognate substrates.

General readings

Liu H., et al. (2002) EMBO J. 21:4699-4708.
Kwasnicka D.A., et al. (2003) J. Biol. Chem. 278:39051-39058.

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  2. Highly Validated (4)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DCPS antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-DCPS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505420) Mouse IgG1 OTIE6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

DCPS antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-DCPS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505626) Mouse IgG1 OTIH8 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

DCPS antibody

Immunoperoxidase of monoclonal antibody to DCPS on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.5 ug/ml] Mouse IgG2b 1G4 Purified Hu, Rt E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DCPS antibody

Immunoperoxidase of monoclonal antibody to DCPS on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse IgG2a 3E5 Purified Hu, Rt E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DCPS antibody

DCPS Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

DCPS antibody

Immunohistochemistry-Paraffin: DCPS Antibody [NBP1-81749] - Immunohistochemical staining of human liver shows strong nuclear positivity in hepatocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DCPS

DCPS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

DCPS (1-337, His-tag)

DCPS Human Purified > 90 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

DCPS (1-337, His-tag)

DCPS Human Purified > 90 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

DCPS

DCPS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DCPS

DCPS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DCPS overexpression lysate

DCPS overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

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