DDIT4 antibody

Principal name

DDIT4 antibody

Alternative names for DDIT4 antibody

DNA-damage-inducible transcript 4, DDIT-4, REDD1, REDD-1, RTP801, HIF-1 responsive protein, Dig2, Protein regulated in development and DNA damage response 1

SwissProt ID

Q08E62 (Bovin), Q8VHZ9 (Rat), Q9D3F7 (Mouse), Q9NX09 (Human)

Gene ID

54541 (DDIT4)

Available reactivities

Ge (Gerbil), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of DDIT4 antibody

REDD1 is a novel transcriptional target of p53 induced following DNA damage. During embryogenesis, REDD1 expression mirrors the tissue-specific pattern of the p53 family member p63, and TP63 null embryos show virtually no expression of REDD1, which is restored in mouse embryo fibroblasts following p63 expression. In differentiating primary keratinocytes, TP63 and REDD1 expression are coordinately downregulated, and ectopic expression of either gene inhibits in vitro differentiation. REDD1 appears to function in the regulation of reactive oxygen species (ROS); TP63 null fibroblasts have decreased ROS levels and reduced sensitivity to oxidative stress, which are both increased following ectopic expression of either TP63 or REDD1. Thus, REDD1 encodes a shared transcriptional target that implicates ROS in the p53-dependent DNA damage response and in p63-mediated regulation of epithelial differentiation.

General readings

Yoshida T., et al. (2010) Nat Med. 16(7):767-73.
Regazzetti C., et al. (2010) J Biol Chem. 285(8):5157-64.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DDIT4 (Center) antibody

Western blot analysis of RTP801 in human kidney tissue lysate with RTP801 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DDIT4 (N-term) antibody

Western blot analysis of RTP801 in 293 cell lysate with RTP801 antibody at (A) 2 and (B) 4 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DDIT4 antibody

Host: Rabbit; Target Name: Ddit4; Sample Tissue: Rat Thymus lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DDIT4 (N-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with DDIT4 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DDIT4 Control Peptide

DDIT4
50 µg / €160.00
  Acris Antibodies GmbH

DDIT4 Control Peptide

DDIT4
50 µg / €160.00
  Acris Antibodies GmbH

DDIT4 antibody

Western Blot analysis of DDIT4 expression in transfected 293T cell line (H00054541-T01) by DDIT4 MaxPab polyclonal antibody.

Lane 1: DDIT4 transfected lysate(25.52 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

DDIT4 antibody

Western Blot analysis of DDIT4 expression in transfected 293T cell line (H00054541-T01) by DDIT4 MaxPab polyclonal antibody.

Lane 1: DDIT4 transfected lysate(25.52 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

DDIT4 antibody

Immunohistochemistry of DDIT4 in mouse kidney tissue with DDIT4 polyclonal antibody ( Cat # PAB13343 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

DDIT4 antibody

Western blot analysis of DDIT4 in 293 cell lysate with DDIT4 polyclonal antibody ( Cat # PAB13346 ) at ( A ) 2 and ( B ) 4 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

DDIT4 antibody

Immunocytochemistry: DDIT4 Antibody [NBP1-22966] - Please see notes section Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

DDIT4 antibody

Immunohistochemistry-Paraffin: DDIT4 Antibody [NBP1-77321] - Mouse kidney tissue with RTP801 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

DDIT4 antibody

Immunohistochemistry-Paraffin: DDIT4 Antibody [NBP1-85211] - staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DDIT4

DDIT4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

DDIT4 (1-232, His-tag)

DDIT4 Human Purified > 90 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

DDIT4 (1-232, His-tag)

DDIT4 Human Purified > 90 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

DDIT4

DDIT4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DDIT4

DDIT4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

DDIT4

DDIT4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DDIT4

DDIT4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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