DDX11 antibody

Principal name

DDX11 antibody

Alternative names for DDX11 antibody

DEAD/H box protein 11, CHL1, CHLR1, KRG2, KRG-2, DEAD box protein 11, Probable ATP-dependent RNA helicase DDX11, Keratinocyte growth factor-regulated gene 2 protein

SwissProt ID

Q6AXC6 (Mouse), Q96FC9 (Human)

Gene ID

1663 (DDX11)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of DDX11 antibody

DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.

General readings

Leman, A.R., et al. J. Cell. Sci. 123 (PT 5), 660-670 (2010).
Farina, A., et al. J. Biol. Chem. 283(30):20925-20936 (2008).
Parish, J.L., et al. Mol. Cell 24(6):867-876 (2006).
Parish, J.L., et al. J. Cell. Sci. 119 (PT 23), 4857-4865 (2006).
Vasa-Nicotera, M., et al. Am. J. Hum. Genet. 76(1):147-151 (2005).

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DDX11 (Center) antibody

Western blot analysis of DDX11 Antibody (Center) Cat.-No AP51215PU-N in mouse Neuro-2a cell line lysates (35ug/lane). This demonstrates the DDX11 antibody detected the DDX11 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DDX11 (C-term) antibody

Western blot analysis of DDX11 Antibody (C-term) Cat.-No AP51216PU-N in K562 cell line lysates (35ug/lane).This demonstrates the DDX11 antibody detected the DDX11 protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DDX11 antibody

DDX11 polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of DDX11 expression in Y-79 ( Cat # L042V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

DDX11 antibody

Immunofluorescence of purified MaxPab antibody to DDX11 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

DDX11 antibody

Immunoperoxidase of monoclonal antibody to DDX11 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse IgG2b 3C1 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DDX11

DDX11 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DDX11

DDX11 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

DDX11

DDX11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DDX11

DDX11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DDX11 293T Cell Transient Overexpression Lysate(Denatured)

DDX11 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

10 Item(s)

per page
  • LinkedIn