DDX20 antibody

Principal name

DDX20 antibody

Alternative names for DDX20 antibody

GEMIN3, GEMIN-3, DP103, DEAD box protein DP 103, Component of gems 3,DEAD box protein 20, Probable ATP-dependent RNA helicase DDX20, DEAD (Asp-Glu-Ala-Asp) box polypeptide 20

SwissProt ID

Q9JJY4 (Mouse), Q9UHI6 (Human)

Gene ID

11218 (DDX20), 1121816 (hemE), 53975

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of DDX20 antibody

The survival of motor neurons (SMN) gene is the disease gene of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The SMN protein is part of a complex containing several proteins, of which one, SIP1 (SMN interacting protein 1), has been characterized so far. The SMN complex is found in both the cytoplasm and in the nucleus, where it is concentrated in bodies called gems. In the cytoplasm, SMN and SIP1 interact with the Sm core proteins of spliceosomal small nuclear ribonucleoproteins (snRNPs), and they play a critical role in snRNP assembly. In the nucleus, SMN is required for pre-mRNA splicing, likely by serving in the regeneration of snRNPs. A DEAD box putative RNA helicase, named Gemin 3 which is another component of the SMN complex, has been identified. Gemin 3 interacts directly with SMN, as well as with SmB, SmD2 and SmD3. Immunolocalization studies using mAbs to Gemin 3 show that it colocalizes with SMN in gems. Gemin 3 binds SMN via its unique COOH-terminal domain, and SMN mutations found in some SMA patients strongly reduce this interaction. The presence of a DEAD box motif in Gemin 3 suggests that it may provide the catalytic activity that plays a critical role in the function of the SMN complex on RNPs.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DDX20 antibody

Western blot analysis of extracts of various cell lines, using DDX20 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

DDX20 antibody

Host: Rabbit; Target Name: Ddx20; Sample Tissue: Rat Kidney lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DDX20 antibody

WB Suggested Anti-Ddx20 Antibody Titration: 0.2-1 ug/ml; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Ms, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

DDX20 antibody

Immunofluorescence of purified MaxPab antibody to DDX20 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

DDX20 antibody

Immunofluorescence of purified MaxPab antibody to DDX20 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

DDX20 antibody

Detection limit for recombinant GST tagged DDX20 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 5H5 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

DDX20 antibody

DDX20 Mouse IgM 2A12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

DDX20 antibody

Gemin 3 Antibody [12H12] Mouse IgG1 12H12 Purified Hu E, F, ICC/IF, IP, P, WB
0.1 ml / €400.00
  Immuquest

DDX20 antibody

Gemin 3 Antibody [12H12] Mouse IgG1 12H12 Purified Hu E, F, ICC/IF, IP, P, WB
50 µl / €360.00
  Immuquest

DDX20 antibody

Western Blot and Immunoprecipitation: DDX20 Antibody [NB100-1801] - Detection of Human DDX20 on HeLa whole cell lystate using NB100-1801. DDX20 was also immunoprecipitated using rabbit anti-DDX20 antibody NB100-1802 and two. Rabbit Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

DDX20 antibody

Western Blot and Immunoprecipitation: DDX20 Antibody [NB100-1802] - Detection of Human DDX20 on HeLa whole cell lystate using NB100-1802. DDX20 was also immunoprecipitated using rabbit anti-DDX20 antibody NB100-1801 and two others. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

DDX20 antibody

Immunohistochemistry-Paraffin: Gemin 3 Antibody [NBP1-84058] - Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

DDX20 antibody

Immunohistochemistry-Paraffin: Gemin 3 Antibody [NBP1-84059] - Immunohistochemical staining of human rectum shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DDX20

DDX20 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DDX20

DDX20 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DDX20

DDX20 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

DDX20

DDX20 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

DDX20

DDX20 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DDX20

DDX20 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

DDX20

DDX20 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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