DDX60 antibody

Principal name

DDX60 antibody

Alternative names for DDX60 antibody

FLJ20035, Probable ATP-dependent RNA helicase DDX60

SwissProt ID

Q8IY21 (Human)

Gene ID

55601 (DDX60)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of DDX60 antibody

DDX60 Antibody: DDX60 is a DEXD/H Box R helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of R exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral R sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, sigling IRF3 and NF-kB-responsive genes in the inte immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated sigling.

General readings

Miyashita M, Oshiumi H, Matsumoto M, et al. DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling. Mol. Cell. Biol. 2011; 31:3802-19.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DDX60 (Center) antibody

Western blot analysis of DDX60 in A20 cell lysate with DDX60 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DDX60 (Center) Control Peptide

DDX60
50 µg / €160.00
  Acris Antibodies GmbH

DDX60 antibody

Immunohistochemistry-Paraffin: DDX60 Antibody [NBP1-91826] - Immunohistochemical staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DDX60

DDX60 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DDX60

DDX60 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

5 Item(s)

per page
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