DEDD2 antibody

Principal name

DEDD2 antibody

Alternative names for DEDD2 antibody

FLAME3, FLAME-3, PSEC0004, FADD-like anti-apoptotic molecule 3, DEDD-2, DNA-binding death effector domain-containing protein 2, DED-containing protein FLAME-3

SwissProt ID

Q8QZV0 (Mouse), Q8WXF8 (Human)

Gene ID

162989 (DEDD2), 67379 (Dedd2)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of DEDD2 antibody

Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain (1). A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified and its over-expression in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD (2). More recently, work has shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD (2,3). Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis (3). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DEDD2 antibody

  Rabbit Polyclonal DEDD2 Antibody  
Western blot analysis of DEDD2 in RAW264.7 cell lysate with DEDD2 antibody at (A) 0.5, (B) 1 and (C) 2 μg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DEDD2 antibody

  Rabbit Polyclonal Anti-DEDD2 Antibody  
WB Suggested Anti-DEDD2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

DEDD2 - human gene knockout kit via CRISPR

DEDD2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DEDD2 - human gene knockout kit via CRISPR

DEDD2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DEDD2 - human gene knockout kit via CRISPR

DEDD2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DEDD2 - human gene knockout kit via CRISPR

DEDD2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dedd2 - mouse gene knockout kit via CRISPR

Dedd2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dedd2 - mouse gene knockout kit via CRISPR

Dedd2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dedd2 - mouse gene knockout kit via CRISPR

Dedd2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dedd2 - mouse gene knockout kit via CRISPR

Dedd2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dedd2 (GFP-tagged) - Mouse death effector domain-containing DNA binding protein 2 (Dedd2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dedd2 (GFP-tagged) - Mouse death effector domain-containing DNA binding protein 2 (Dedd2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dedd2 (Myc-DDK-tagged) - Mouse death effector domain-containing DNA binding protein 2 (Dedd2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dedd2 (Myc-DDK-tagged) - Mouse death effector domain-containing DNA binding protein 2 (Dedd2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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