DEDD2 antibody

Principal name

DEDD2 antibody

Alternative names for DEDD2 antibody

FLAME3, FLAME-3, PSEC0004, FADD-like anti-apoptotic molecule 3, DEDD-2, DNA-binding death effector domain-containing protein 2, DED-containing protein FLAME-3

SwissProt ID

Q8QZV0 (Mouse), Q8WXF8 (Human)

Gene ID

162989 (DEDD2)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of DEDD2 antibody

Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain (1). A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified and its over-expression in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD (2). More recently, work has shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD (2,3). Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis (3). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DEDD2 antibody

Western blot analysis of DEDD2 in RAW264.7 cell lysate with DEDD2 antibody at (A) 0.5, (B) 1 and (C) 2 μg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DEDD2 antibody

WB Suggested Anti-DEDD2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DEDD2 Control Peptide

DEDD2
50 µg / €160.00
  Acris Antibodies GmbH

DEDD2 antibody

DEDD2 Rabbit Bov, Hu, Ms, Rt C, IP, P
50 µl / €390.00
  Abnova Taiwan Corp.

DEDD2 antibody

Western blot analysis of DEDD2 in RAW264.7 cell lysate with DEDD2 polyclonal antibody ( Cat # PAB12889 ) at 0.5, 1 and 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

DEDD2 (Center) antibody

Human Lung; WB Suggested Anti-DEDD2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Lung; DEDD2 antibody - middle region (ARP52558_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

DEDD2 antibody

DEDD2 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €360.00
  Novus Biologicals Inc.

DEDD2 antibody

DEDD2 Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

DEDD2 antibody

Immunohistochemistry-Paraffin: DEDD2 Antibody [NBP1-91827] - Immunohistochemical staining of human kidney shows moderate membranous and cytoplasmic positivity in renal tubules. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

DEDD2 antibody

Immunohistochemistry-Paraffin: DEDD2 Antibody [NBP1-91828] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DEDD2

DEDD2 Human
2 µg / €300.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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