Defensin beta 2 antibody

Principal name

Defensin beta 2 antibody

Alternative names for Defensin beta 2 antibody

Beta-defensin 4A, Beta-defensin 2, BD-2, hBD-2, DEFB102, DEFB2, Skin-antimicrobial peptide 1, DEFB4B, DEFB4A

SwissProt ID

O15263 (Human), O19039 (Sheep), O88514, P46160 (Bovin), P82020 (Mouse)

Gene ID

100289462 (DEFB4B), 1673 (DEFB4A), 13215 (Defb2), 64389 (Defb4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Sheep, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Neutralisation (NEUT), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Radioimmunoassay (R)

Background of Defensin beta 2 antibody

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Defensin beta 2 antibody

Defensin beta 2 Rabbit Purified Hu E, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Defensin beta 2 antibody

  Biotinylated Anti-Human BD-2 Goat Polyclonal Antibody  
To detect hBD-2 by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant hBD-2. Goat IgG Purified Hu E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Defensin beta 2 antibody

  Anti-Human BD-2 Goat Polyclonal Antibody  
To detect hBD-2 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human BD-2 (TA328263) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hBD-2. Goat IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Defensin beta 2 antibody

  Rabbit Polyclonal Anti-DEFB4A Antibody  
WB Suggested Anti-DEFB4A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Placenta Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Defensin beta 2 (4-41) antibody

Immunohistochemical staining of Beta-Defensin-2 in Paraffin Section of Human colon resection tissue. Antigen retrieval was performed in citric acid (0.01M, pH6) twice for 7 min and in 0.1% Trypsin for 5 min. The section was incubated with AM02221PU (1/2000) for 1 h and detected using Alkaline Phophatase anti-Alkaline Phophatase method. New fuchsin was used as the chromogen. The section was counterstained with hematoxylin. AM02221PU stains colonic epithelial enterocytes in ulcerative colitis patients. 
Langhorst J et al. (2009) Am. J. Gastroenterol 104(2): 404-410. Mouse IgG1 L12-4C-C2 Purified Hu E, P, WB
0.1 mg / €500.00
  Acris Antibodies GmbH

Defensin beta 2 (4-41) antibody

Immunohistochemical staining of Beta-Defensin-2 in Paraffin Section of Human colon resection tissue. Antigen retrieval was performed in citric acid (0.01M, pH6) twice for 7 min and in 0.1% Trypsin for 5 min. The section was incubated with AM02221PU (1/2000) for 1 h and detected using Alkaline Phophatase anti-Alkaline Phophatase method. New fuchsin was used as the chromogen. The section was counterstained with hematoxylin. AM02221PU stains colonic epithelial enterocytes in ulcerative colitis patients. 
Langhorst J et al. (2009) Am. J. Gastroenterol 104(2): 404-410. Mouse IgG1 L12-4C-C2 Purified Hu E, P, WB
10 µg / €180.00
  Acris Antibodies GmbH

Defensin beta 2 (4-41) antibody

Defensin beta 2 Sheep Ig Fraction Hu E
0.1 mg / €540.00
  Acris Antibodies GmbH

Defensin beta 2 (4-41) antibody

Defensin beta 2 Sheep Ig Fraction Hu E
10 µg / €190.00
  Acris Antibodies GmbH

Defensin beta 2 (4-41) antibody

Defensin beta 2 Sheep Serum Hu E
0.1 ml / €400.00
  Acris Antibodies GmbH

Defensin beta 2 (4-41) antibody

Defensin beta 2 Sheep Serum Hu E
20 µl / €160.00
  Acris Antibodies GmbH

Defensin beta 2 antibody

Direct ELISA using Defensin beta 2 Antibody Cat.-No PP1125B Goat Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Defensin beta 2 antibody

Direct ELISA using Defensin beta 2 Antibody Cat.-No PP1125B Goat Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Defensin beta 2 antibody

Sandwich ELISA using Defensin beta 2 Antibody Cat.-No PP1125P Goat Aff - Purified Hu E, NEUT, WB
50 µg / €230.00
  Acris Antibodies GmbH

Defensin beta 2 antibody

Sandwich ELISA using Defensin beta 2 Antibody Cat.-No PP1125P Goat Aff - Purified Hu E, NEUT, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Defb2 - mouse gene knockout kit via CRISPR

Defb2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Defb2 - mouse gene knockout kit via CRISPR

Defb2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Defb2 - mouse gene knockout kit via CRISPR

Defb2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Defb2 - mouse gene knockout kit via CRISPR

Defb2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

DEFB4A - human gene knockout kit via CRISPR

DEFB4A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DEFB4A - human gene knockout kit via CRISPR

DEFB4A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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