DEGS2 antibody

Principal name

DEGS2 antibody

Alternative names for DEGS2 antibody

Degenerative spermatocyte homolog 2, C14orf66, DES2, Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2

SwissProt ID

Q0II71 (Bovin), Q564G3 (Rat), Q6QHC5 (Human), Q8R2F2 (Mouse)

Gene ID

123099 (DEGS2)

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of DEGS2 antibody

Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9. Belongs to the fatty acid desaturase family. DEGS subfamily. Highly expressed in skin, intestine and kidney.

General readings

1. Mizutani, Y., et al. "Identification of the human sphingolipid C4-hydroxylase, hDES2, and its upregulation
during keratinocyte differentiation."; FEBS Lett. 563:93-97(2004).
2. Omae, F., et al. "DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine." Biochem J. 2004 May 1;379(Pt 3):687-95.
3. Omae, F. et al. "Identification of an essential sequence for dihydroceramide C-4 hydroxylase activity of mouse DES2." FEBS Lett. 2004 Oct 8;576(1-2):63-7.
4. Enomoto, A., et al. "Dihydroceramide:sphinganine C-4-hydroxylation requires Des2 hydroxylase and the membrane form of cytochrome b5." Biochem J. 2006 Jul 15;397(2):289-95.

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DEGS2 Control Peptide

DEGS2 Purified
50 µg / €210.00
  Acris Antibodies GmbH

DEGS2 antibody

DEGS2 Rabbit Aff - Purified Hu WB
10 Blots / €480.00
  Acris Antibodies GmbH

DEGS2 antibody

DEGS2 Rabbit Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

DEGS2 (C-term) antibody

Formalin fixed and paraffin embedded human kidney tissue reacted with DEGS2 Antibody (C-term) Cat.-No AP51233PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DEGS2 antibody

Western blot using DEGS2 polyclonal antibody on human kidney cell lysate at 15 µg/lane. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DEGS2

DEGS2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DEGS2

DEGS2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DEGS2 overexpression lysate

DEGS2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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