Delta-like protein 1 antibody

Principal name

Delta-like protein 1 antibody

Alternative names for Delta-like protein 1 antibody

DLL1, Drosophila Delta homolog 1, Delta1, H-Delta-1

SwissProt ID

O00548 (Human), P97677 (Rat), Q61483 (Mouse)

Gene ID

28514 (DLL1), 13388

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Chk (Chicken), Bov (Bovine), African clawed frog, Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse, Hamster

Available applications

Enzyme Immunoassay (E), Flow Cytometry (F), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of Delta-like protein 1 antibody

Human soluble DLL-1 comprises the extracellular signaling domain of DLL-1, a member of the Delta/Serrate/Lag-2 (DSL) family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. It is expressed primarily in the heart, pancreas and epidermis. DLL-1 functions to specifically activate the Notch-1 and Notch-2 receptors. Proteolytic cleavage of DLL-1 produces a secreted extracellular domain, sDLL-1, that interacts with Notch receptors expressed on adjacent cells. Notch signaling plays an essential role in controlling cell fate decisions during prenatal development and postnatal stem cell renewal, and differentiation in many tissues. Human sDLL-1 blocks monocyte differentiation into macrophages, but permits differentiation into dendritic cells. In hematopoietic progenitor cells, hsDLL-1, suppresses differentiation into B-cells, while promoting differentiation into T-cells and NK cell precursors. In cell culture, human sDLL-1 has been shown to promote expansion of hematopoietic progenitor cells and suppress apoptosis by inhibiting differentiation. Overexpression of Notch receptors appears to inhibit differentiation in several mammalian cell lines, and increasing evidence suggests that Notch signaling is frequently downregulated in human malignancies. The human DLL-1 gene consists of a 528 amino acid extracellular domain with one DSL domain, eight EGF-like repeats, a 23 amino acid transmembrane domain, and a 155 amino acid cytoplasmic domain. The calculated molecular weight of Recombinant Human sDLL-1 is 56.3 kDa.

General readings

Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D.
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells.
2008 Mar 2 (3): 219-29.
PMID: 18371447

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Delta-like protein 1 antibody

TA305657 (0.3ug/ml) staining of Rat Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Delta-like protein 1 antibody

Staining of Delta-like 1-transfected CHO cells with 0.25 ug of Armenian Hamster IgG Isotype Control Purified (blue histogram) or 0.25 ug of Anti-Mouse DLL1 (delta-like 1) Purified (purple histogram).  Total viable cells were used for analysis. Hamster HMD1-5 Purified Ms F, P
0.1 mg / €150.00
  OriGene Technologies, Inc.

Delta-like protein 1 antibody

WB Suggested Anti-DLL1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Delta-like protein 1 (155-173) antibody

Figure 1. Staining DLL1 (Delta-1) in Brain by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €470.00
  Acris Antibodies GmbH

Delta-like protein 1 (155-173) antibody

Delta-like protein 1 Rabbit IgG Aff - Purified Chk, Hu, Ms, Rt E
0.1 mg / €440.00
  Acris Antibodies GmbH

Delta-like protein 1 antibody

Delta-like protein 1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

Delta-like protein 1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

Delta-like protein 1 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

Detection limit for recombinant GST tagged DLL1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 4F8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

Detection limit for recombinant GST tagged DLL1 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 4F9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

Delta-like protein 1 Rabbit Chk, Hu, Ms, Rt E, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

DLL1 polyclonal antibody ( Cat # PAB12816 ) ( 0.3µg/ml ) staining of rat heart lysate ( 35µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Delta-like protein 1 antibody

Hela; Host: Rabbit. Target Name:DLL1. Sample Tissue:Hela. Lane A: Primary Antibody . Lane B: Primary Antibody + Blocking Peptide . Primary Antibody Concentration:1ug/ml. Peptide Concentration: 5ug/ml. Lysate Quantity: 25ug/lane/lane. Gel Concentration: 0.12.; DLL1 antibody - N-terminal region (ARP46625_P050) in Hela cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

Delta-like protein 1 antibody

Delta-like protein 1 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

Delta-like protein 1 antibody

NB 600-628 Delta 1 antibody Rabbit IgG Aff - Purified Chk, Hu, Ms, Rt E, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

Delta-like protein 1 antibody

Western blot: DLL1 Antibody [NBP1-26400]-(0.3ug/ml) staining of Rat Heart lysate (35ug protein in RIPA buffer) Goat IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Delta-like protein 1 antibody

Western Blot: DLL1 Antibody [NBP1-59217] - This Anti-DLL1 antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Delta-like protein 1

Delta-like protein 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Delta-like protein 1

Delta-like protein 1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 25 µg / €399.00

Special Price: 25 µg / €239.00

  OriGene Technologies, Inc.

Delta-like protein 1

Delta-like protein 1 Human Purified > 95 % pure by SDS-PAGE and HPLC analyses HEK293 cells
25 µg / €230.00
  Acris Antibodies GmbH

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