Dematin antibody

Principal name

Dematin antibody

Alternative names for Dematin antibody

EPB49, DMT, Erythrocyte membrane protein band 4.9

SwissProt ID

Q08495 (Human), Q08DM1 (Bovin), Q9WV69 (Mouse)

Gene ID

2039 (EPB49)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of Dematin antibody

Caldesmon, filamin 1, nebulin, villin, plastin, ADF, gelsolin, Dematin, and cofilin are differentially expressed actin binding proteins. Dematin is a bundling protein of the erythrocyte membrane skeleton. Dematin is localized to the spectrin-actin junctions, and its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase. It may also play a role in the regulation of cell shape, implying a role in tumorigenesis. Dematin is a trimeric protein containing two subunits of 48 kDa and one subunit of 52 kDa. It is localized to the heart, brain, lung, skeletal muscle, and kidney. The Dematin gene is located on human chromosome 8p21.1, a region frequently deleted in prostate cancer, and mouse chromosome 14.

General readings

Vugmeyster, L., et al. J. Biomol. NMR 47(2):155-162(2010)
Chen, L., et al. Protein Sci. 18(3):629-636(2009)
Vugmeyster, L., et al. J. Biomol. NMR 43(1):39-50(2009)
Vermeulen, W., et al. J. Mol. Biol. 359(5):1277-1292(2006)
Frank, B.S., et al. J. Biol. Chem. 279(9):7909-7916(2004).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dematin antibody

Host: Rabbit; Target Name: DMTN; Sample Tissue: Hela Whole cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Dematin antibody

Western blot analysis of Dematin expression in HeLa whole cell Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dematin antibody

AP20222PU-N Dematin antibody staining of Paraffin-Embedded Human heart tissue by Immunohistochemistry. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Dematin (Center) antibody

Western blot analysis of Dematin Antibody Cat.-No AP51441PU-N in Y79 cell line lysates (35ug/lane). This demonstrates the Dematin antibody detected the Dematin protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Dematin antibody

EPB49 MaxPab polyclonal antibody. Western Blot analysis of EPB49 expression in rat brain. Mouse Serum Hu, Rt E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Dematin antibody

EPB49 MaxPab polyclonal antibody. Western Blot analysis of EPB49 expression in rat brain. Mouse Purified Hu, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Dematin pSer403 antibody

Immunohistochemistry analysis of paraffin-embedded human heart, using Dematin (Phospho-Ser403) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
50 µg / €205.00
  Assay Biotech

Dematin pSer403 antibody

Immunohistochemistry analysis of paraffin-embedded human heart, using Dematin (Phospho-Ser403) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €310.00
  Assay Biotech

Dematin antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Dematin (Ab-403) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

Dematin antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Dematin (Ab-403) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

Dematin (Center) antibody

Human Jurkat; WB Suggested Anti-EPB49 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Jurkat Whole Cell; EPB49 antibody - middle region (ARP61705_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Dematin antibody

Dematin Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Dematin antibody

Dematin Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Dematin antibody

Immunohistochemistry-Paraffin: Dematin Antibody [NBP1-85007] - Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Dematin (transcript variant 1)

Dematin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Dematin (transcript variant 3)

Dematin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Dematin (transcript variant 2)

Dematin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Dematin

Dematin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Dematin

Dematin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DMTN overexpression lysate

DMTN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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