Deoxycytidine kinase antibody

Principal name

Deoxycytidine kinase antibody

Alternative names for Deoxycytidine kinase antibody

DCK, MGC117410, MGC138632

SwissProt ID

P27707 (Human), P43346 (Mouse), P48769 (Rat), Q3MHR2 (Bovin)

Gene ID

1633 (DCK), 13178 (Dck), 79127

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Deoxycytidine kinase antibody

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Radu CG., et al. (2010) Proc Natl Acad Sci U S A. 107(12):5551-6.
Ribeiro R., et al. (2007) J Pharmacol Exp Ther. 323(3):935-45.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Deoxycytidine kinase antibody

  DCK mouse monoclonal antibody, clone OTI16E12 (formerly 16E12)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCK (RC210767, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCK. Mouse IgG1 OTI16E12 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Deoxycytidine kinase antibody

  Rabbit Polyclonal antibody to DCK (deoxycytidine kinase)  
Sample (30 ug of whole cell lysate). A: A431. 12% SDS PAGE. TA308454 diluted at 1:5000. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Deoxycytidine kinase antibody

  Rabbit anti-DCK Polyclonal Antibody  
Western blot analysis of extracts of WiDr cell lines, using DCK antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Deoxycytidine kinase antibody

  DCK mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)  
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-DCK mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502688) Mouse IgG2a OTI3F5 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Deoxycytidine kinase antibody

  DCK mouse monoclonal antibody, clone OTI16G6 (formerly 16G6)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-DCK mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502698) Mouse IgG1 OTI16G6 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Deoxycytidine kinase antibody

  DCK mouse monoclonal antibody, clone OTI15E12 (formerly 15E12)  
Anti-DCK mouse monoclonal antibody (TA502713) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DCK(RC210767). Mouse IgG2a OTI15E12 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Deoxycytidine kinase antibody

  Rabbit Polyclonal Anti-DCK Antibody  
WB Suggested Anti-DCK Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: 721_B cell lysateDCK is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Deoxycytidine kinase antibody

  Rabbit Polyclonal Anti-DCK Antibody  
WB Suggested Anti-DCK Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Deoxycytidine kinase antibody

  Rabbit Polyclonal Anti-DCK Antibody  
Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Mouse heart tissue, Primary antibody: (DCK Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Deoxycytidine kinase antibody

  Rabbit Polyclonal DCK Antibody  
ELISA: DCK Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Deoxycytidine kinase (N-term) antibody

Brain, cortex: Formalin-Fixed Paraffin Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Deoxycytidine kinase (C-term) antibody

The anti-DCK Pab is used in Western blot to detect DCK in mouse intestine tissue lysate. Rabbit Ig Purified Hu, Ms IP, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Dck - mouse gene knockout kit via CRISPR

Dck - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dck - mouse gene knockout kit via CRISPR

Dck - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dck - mouse gene knockout kit via CRISPR

Dck - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dck - mouse gene knockout kit via CRISPR

Dck - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Deoxycytidine kinase

  Recombinant protein of human deoxycytidine kinase (DCK)  
Deoxycytidine kinase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Deoxycytidine kinase (full length, C-term DDK tag)

  Recombinant protein of human deoxycytidine kinase (DCK), full length, with C-terminal DDK tag,expressed in sf9 cells  
Deoxycytidine kinase Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Deoxycytidine kinase (N-term polyhistidine tag)

  Recombinant protein of human deoxycytidine kinase (DCK), full length with N-terminal polyhistidine tag, expressed in sf9 cells.  
Deoxycytidine kinase Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Deoxycytidine kinase (1-260, His-tag)

Deoxycytidine kinase Human Purified > 90 % E. coli
0.5 mg / €1,000.00
  Acris Antibodies GmbH

Items 1 to 20 of 24 total

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