Deoxyribonuclease-1 antibody

Principal name

Deoxyribonuclease-1 antibody

Alternative names for Deoxyribonuclease-1 antibody

DNASE1, DNL1, DRNI, Deoxyribonuclease I, DNase I

SwissProt ID

O18998 (Rabit), P00639 (Bovin), P11936 (Pig), P11937 (Sheep), P21704 (Rat), P24855 (Human), P49183 (Mouse), Q4AEE3 (Horse), Q767J3 (Canfa), Q9YGI5 (Chick)

Gene ID

282217 (DNASE1), 1773

Available reactivities

Bov (Bovine), Hu (Human), Can (Canine), Rb (Rabbit), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), Immunodiffusion (ID), Immunoprecipitation (IP), Radioimmunoassay (R), Paraffin Sections (P)

Background of Deoxyribonuclease-1 antibody

Deoxyribonuclease I (EC 3.1.21.1) gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized.

DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Deoxyribonuclease-1 antibody

Sample (30 ug of whole cell lysate). A: MOLT4 . 10% SDS PAGE. TA308546 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Deoxyribonuclease-1 antibody

WB Suggested Anti-DNASE1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: PANC1 cell lysate.DNASE1 is supported by BioGPS gene expression data to be expressed in PANC1 Rabbit IgG Purified Bov, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Deoxyribonuclease-1 antibody

Western Blot testing of anti-bovine DNaseI monoclonal antibody (7B12). Line 1: PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2: Recombinant bovine DNaseI expressed into the supernatant of CHO cell culture medium. 10 µl of cell culture supernatant was loaded into the gel. Mouse IgG1 7B12 Aff - Purified Bov, Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Western Blot testing of anti-bovine DNaseI monoclonal antibody (6D5). Line 1: PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2: Recombinant bovine DNaseI expressed into the supernatant of CHO cell culture medium. 10 µl of cell culture supernatant was loaded into the gel. Mouse IgG1 6D5 Aff - Purified Bov, Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Western Blot testing of anti-Bovine DNaseI monoclonal antibody (4B10). Line 1: PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2: Recombinant bovine DNaseI expressed into the supernatant of CHO cell culture medium. 10 µl of cell culture supernatant was loaded into the gel. Mouse IgG1 4B10 Aff - Purified Bov, Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit IgG Aff - Purified Bov Dot, E, ICC/IF, ID, IP, R, WB
1 mg / €430.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 (1-252) antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Can, Hu, Rb P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit Serum Bov E, WB
2 ml / €1,150.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit Biotin Bov E, IP, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit HRP Bov E, IP, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit Ig Fraction Bov E, IP, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Deoxyribonuclease-1 antibody

Western Blot analysis of DNASE1 expression in transfected 293T cell line (H00001773-T01) by DNASE1 MaxPab polyclonal antibody.

Lane 1: DNASE1 transfected lysate(31.02 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit Bov WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Deoxyribonuclease-1 antibody

Human PANC1; WB Suggested Anti-DNASE1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: PANC1 cell lysate. DNASE1 is supported by BioGPS gene expression data to be expressed in PANC1.; DNASE1 antibody - N-terminal region (ARP46588_P050) in Human PANC1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Deoxyribonuclease-1 antibody

Deoxyribonuclease-1 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Deoxyribonuclease-1 antibody

Immunohistochemistry-Paraffin: DNASE1 Antibody [NBP1-84999] - Immunohistochemical staining of human colon shows strong positivity in goblet cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Deoxyribonuclease-1

Deoxyribonuclease-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Deoxyribonuclease-1

Deoxyribonuclease-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Deoxyribonuclease-1

Deoxyribonuclease-1 Bovine
5 mg / €200.00
  Abnova Taiwan Corp.

Deoxyribonuclease-1

Deoxyribonuclease-1 Bovine
11 mg / €220.00
  Abnova Taiwan Corp.

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