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Deoxyribonuclease-2-beta antibody

Principal name

Deoxyribonuclease-2-beta antibody

Alternative names for Deoxyribonuclease-2-beta antibody

DNASE2B, DLAD, Deoxyribonuclease II beta, DNase2-like acid DNase, DNase II-like acid DNase, Endonuclease DLAD

SwissProt ID

Q8WZ79 (Human), Q9QY48 (Mouse), Q9QZK9 (Rat)

Gene ID

58511 (DNASE2B), 56629 (Dnase2b), 59296

Ncbi ID

9606, NP_067056, NP_490649, NP_067056.2, NM_019957, NM_021664, NM_021233, NM_058248

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Deoxyribonuclease-2-beta antibody

DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

General readings

Nishimoto,S., (2003) Nature 424 (6952), 1071-1074

ARP42593_P050 - Deoxyribonuclease-2-beta

Human Muscle; WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Muscle; DNASE2B antibody - N-terminal region (ARP42593_P050) in Human Muscle cells using Western Blot

ARP42593_P050

ARP42596_P050 - Deoxyribonuclease-2-beta

Human Placenta; WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Placenta; DNASE2B antibody - middle region (ARP42596_P050) in Human Placenta cells using Western Blot

ARP42596_P050

ARP42597_P050 - Deoxyribonuclease-2-beta

Human 293T; WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 293T cell lysate; DNASE2B antibody - middle region (ARP42597_P050) in Human 293T cells using Western Blot

ARP42597_P050

WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Placenta

TA329460

WB Suggested Anti-DNASE2B Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysate

TA329459

WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle

TA329458

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA329458	Deoxyribonuclease-2-beta antibody
	Rabbit Polyclonal anti-DNASE2B antibody
	Rabbit	IgG	Purified	Hu	WB	50 µg / €325.00
						OriGene Technologies, Inc.
TA329459	Deoxyribonuclease-2-beta antibody
	Rabbit Polyclonal anti-DNASE2B antibody
	Rabbit	IgG	Purified	Hu	WB	0.1 mg / €325.00
						OriGene Technologies, Inc.
TA329460	Deoxyribonuclease-2-beta antibody
	Rabbit Polyclonal anti-DNASE2B antibody
	Rabbit	IgG	Purified	Hu	WB	50 µg / €325.00
						OriGene Technologies, Inc.
TA329461	Deoxyribonuclease-2-beta antibody
	Rabbit Polyclonal anti-DNASE2B antibody
	Rabbit	IgG	Purified	Hu	WB	50 µg / €325.00
						OriGene Technologies, Inc.

CRISPR

Catalog No.	Species	Donor Vector
KN212192	DNASE2B - human gene knockout kit via CRISPR
	Human	GFP-Puro	1 kit / €1,200.00
			OriGene Technologies, Inc.
KN212192BN	DNASE2B - human gene knockout kit via CRISPR
	Human	mBFP-Neo	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN212192LP	DNASE2B - human gene knockout kit via CRISPR
	Human	Luciferase-Puro	1 kit / €1,290.00
			OriGene Technologies, Inc.
KN212192RB	DNASE2B - human gene knockout kit via CRISPR
	Human	RFP-BSD	1 kit / €1,290.00
			OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.
RC212192L2V	Lenti ORF particles, DNASE2B (mGFP-tagged) - Human deoxyribonuclease II beta (DNASE2B), transcript variant 1, 200 uL, >10^7 TU/mL
		200 µl / €1,050.00
		OriGene Technologies, Inc.

RC214291L2V	Lenti ORF particles, DNASE2B (mGFP-tagged)-Human deoxyribonuclease II beta (DNASE2B), transcript variant 2, 200 uL, >10^7 TU/mL
		200 µl / €880.00
		OriGene Technologies, Inc.

RC212192L1V	Lenti ORF particles, DNASE2B (Myc-DDK tagged) - Human deoxyribonuclease II beta (DNASE2B), transcript variant 1 , 200 uL, >10^7 TU/mL
		200 µl / €940.00
		OriGene Technologies, Inc.

RC214291L1V	Lenti ORF particles, DNASE2B (Myc-DDK-tagged)-Human deoxyribonuclease II beta (DNASE2B), transcript variant 2, 200 uL, >10^7 TU/mL
		200 µl / €780.00
		OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.
MR205393L2V	Lenti ORF particles, Dnase2b (GFP-tagged) - Mouse deoxyribonuclease II beta (Dnase2b), 200 uL, >10^7 TU/mL
		200 µl / €880.00
		OriGene Technologies, Inc.

MR205393L1V	Lenti ORF particles, Dnase2b (Myc-DDK-tagged) - Mouse deoxyribonuclease II beta (Dnase2b), 200 uL, >10^7 TU/mL
		200 µl / €780.00
		OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.
RR212127L2V	Lenti ORF particles, Dnase2b (GFP-tagged ORF) - Rat deoxyribonuclease II beta (Dnase2b), 200 uL, >10^7 TU/mL
		200 µl / €880.00
		OriGene Technologies, Inc.

RR212127L1V	Lenti ORF particles, Dnase2b (Myc-DDK-tagged ORF) - Rat deoxyribonuclease II beta (Dnase2b), 200 uL, >10^7 TU/mL
		200 µl / €780.00
		OriGene Technologies, Inc.

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