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Deoxyribonuclease-2-beta antibody

Principal name

Deoxyribonuclease-2-beta antibody

Alternative names for Deoxyribonuclease-2-beta antibody

DNASE2B, DLAD, Deoxyribonuclease II beta, DNase2-like acid DNase, DNase II-like acid DNase, Endonuclease DLAD

SwissProt ID

Q8WZ79 (Human), Q9QY48 (Mouse), Q9QZK9 (Rat)

Gene ID

58511 (DNASE2B)

Ncbi ID

9606, NP_067056, NP_490649, NP_067056.2

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Deoxyribonuclease-2-beta antibody

DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

General readings

Nishimoto,S., (2003) Nature 424 (6952), 1071-1074

ARP42593_P050 - Deoxyribonuclease-2-beta

Human Muscle; WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Muscle; DNASE2B antibody - N-terminal region (ARP42593_P050) in Human Muscle cells using Western Blot

ARP42593_P050

ARP42596_P050 - Deoxyribonuclease-2-beta

Human Placenta; WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Placenta; DNASE2B antibody - middle region (ARP42596_P050) in Human Placenta cells using Western Blot

ARP42596_P050

Immunofluorescence analysis of methanol-fixed A549, using DNASE2B(GTX119205) antibody at 1:500 dilution.

GTX119205

Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE GTX119205 diluted at 1:1000

GTX119205

Sample (30 ug of whole cell lysate) A: HCT116 12% SDS PAGE GTX119206 diluted at 1:500

GTX119206

ARP42597_P050 - Deoxyribonuclease-2-beta

Human 293T; WB Suggested Anti-DNASE2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 293T cell lysate; DNASE2B antibody - middle region (ARP42597_P050) in Human 293T cells using Western Blot

ARP42597_P050

Western Blot: DNASE2B Antibody [NBP1-62279] - This Anti-DNASE2B antibody was used in Western Blot of Placenta tissue lysate at a concentration of 1ug/ml.

NBP1-62279

Western Blot: DNASE2B Antibody [NBP1-69308] - This Anti-DNASE2B antibody was used in Western Blot of Fetal Muscle tissue lysate at a concentration of 1ug/ml.

NBP1-69308

Immunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using 22652-1-AP( DNASE2B Antibody) at dilution of 1:50 (under 10x lens)

22652-1-AP

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 22652-1-AP( DNASE2B Antibody) at dilution of 1:50 (under 10x lens)

22652-1-AP

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 22652-1-AP( DNASE2B Antibody) at dilution of 1:50 (under 40x lens)

22652-1-AP

Immunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using 22652-1-AP( DNASE2B Antibody) at dilution of 1:50 (under 40x lens)

22652-1-AP

Immunofluorescent analysis of A549 cells using 22652-1-AP( DNASE2B Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG

22652-1-AP

Jurkat cells were subjected to SDS PAGE followed by western blot with 22652-1-AP( DNASE2B Antibody) at dilution of 1:2000

22652-1-AP

A549 cells were subjected to SDS PAGE followed by western blot with 22652-1-AP( DNASE2B Antibody) at dilution of 1:2000

22652-1-AP

Primary Antibodies

Catalog No.	Host	Pres.	React.	Applications
H00058511-A01	Deoxyribonuclease-2-beta antibody
	Mouse	Serum	Hu	E, WB	50 µl / €290.00
					Abnova Taiwan Corp.
ARP42593_P050	Deoxyribonuclease-2-beta antibody
	Rabbit	Aff - Purified	Bov, Hu	WB	50 µg / €350.00
					AVIVA Systems Biology
ARP42596_P050	Deoxyribonuclease-2-beta antibody
	Rabbit	Aff - Purified	Bov, Hu	WB	50 µg / €350.00
					AVIVA Systems Biology
ARP42597_P050	Deoxyribonuclease-2-beta antibody
	Rabbit	Aff - Purified	Bov, Hu, Ms, Rt	WB	50 µg / €350.00
					AVIVA Systems Biology
NBP1-62279	Deoxyribonuclease-2-beta antibody
	Rabbit	Aff - Purified	Hu	WB	50 µg / €440.00
					Novus Biologicals Inc.
NBP1-69308	Deoxyribonuclease-2-beta antibody
	Rabbit	Aff - Purified	Hu	WB	50 µg / €440.00
					Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No.	Species	Pres.	Purity	Source
H00058511-P01-10	Deoxyribonuclease-2-beta
	Human	Purified	12.5% SDS-PAGE Stained with Coomassie Blue.		10 µg / €380.00
					Abnova Taiwan Corp.
H00058511-P01-25	Deoxyribonuclease-2-beta
	Human	Purified	12.5% SDS-PAGE Stained with Coomassie Blue.		25 µg / €510.00
					Abnova Taiwan Corp.
H00058511-Q01-10	Deoxyribonuclease-2-beta
	Human		12.5% SDS-PAGE Stained with Coomassie Blue.	in vitro transl.	10 µg / €380.00
					Abnova Taiwan Corp.
H00058511-Q01-25	Deoxyribonuclease-2-beta
	Human		12.5% SDS-PAGE Stained with Coomassie Blue.	in vitro transl.	25 µg / €510.00
					Abnova Taiwan Corp.

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