Desmocollin-3 antibody

Principal name

Desmocollin-3 antibody

Alternative names for Desmocollin-3 antibody

Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4, Cadherin family member 3

SwissProt ID

P55850 (Mouse), Q14574 (Human), Q28060 (Bovin)

Gene ID

1825 (DSC3), 13507 (Dsc3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Desmocollin-3 antibody

DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)
Spindler, V., et al. J. Biol. Chem. 284(44):30556-30564(2009)
Ayub, M., et al. Am. J. Hum. Genet. 85(4):515-520(2009)
Aoyama, Y., et al. Exp. Dermatol. 18(4):404-408(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Desmocollin-3 antibody

Desmocollin-3 Mouse IgG1 Dsc3-U114 Purified Hu C, P, WB
50 µg / €340.00
  OriGene Technologies GmbH

Desmocollin-3 (C-term) antibody

Western blot analysis of DSC3 Antibody (C-term) Cat.-No AP51323PU-N in mouse spleen tissue lysates (35ug/lane). This demonstrates the DSC3 antibody detected the DSC3 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DSC3 (mGFP-tagged)-Human desmocollin 3 (DSC3), transcript variant Dsc3a, 200 uL, >10^7 TU/mL

Lenti ORF particles, DSC3 (mGFP-tagged)-Human desmocollin 3 (DSC3), transcript variant Dsc3a, 200 uL, >10^7 TU/mL  
200 µl / €1,937.00
  OriGene Technologies, Inc.

Lenti ORF particles, DSC3 (mGFP-tagged)-Human desmocollin 3 (DSC3), transcript variant Dsc3b, 200 uL, >10^7 TU/mL

Lenti ORF particles, DSC3 (mGFP-tagged)-Human desmocollin 3 (DSC3), transcript variant Dsc3b, 200 uL, >10^7 TU/mL  
200 µl / €1,844.00
  OriGene Technologies, Inc.

Lenti ORF particles, DSC3 (Myc-DDK-tagged)-Human desmocollin 3 (DSC3), transcript variant Dsc3b, 200 uL, >10^7 TU/mL

Lenti ORF particles, DSC3 (Myc-DDK-tagged)-Human desmocollin 3 (DSC3), transcript variant Dsc3b, 200 uL, >10^7 TU/mL  
200 µl / €1,659.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dsc3 (GFP-tagged) - Mouse desmocollin 3 (Dsc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dsc3 (GFP-tagged) - Mouse desmocollin 3 (Dsc3), 200 uL, >10^7 TU/mL  
200 µl / €1,700.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dsc3 (Myc-DDK-tagged) - Mouse desmocollin 3 (Dsc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dsc3 (Myc-DDK-tagged) - Mouse desmocollin 3 (Dsc3), 200 uL, >10^7 TU/mL  
200 µl / €1,525.00
  OriGene Technologies, Inc.

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