Desmoglein-2 antibody

Principal name

Desmoglein-2 antibody

Alternative names for Desmoglein-2 antibody

DSG2, CDHF5,HDGC, Cadherin family member 5

SwissProt ID

O55111 (Mouse), Q14126 (Human)

Gene ID

1829 (DSG2)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Desmoglein-2 antibody

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1、Arnemann J, Spurr NK, Magee AI, Buxton RS (Jul 1992). "The human gene (DSG2) coding for HDGC, a second member of the desmoglein subfamily of the desmosomal cadherins, is, like DSG1 coding for desmoglein DGI, assigned to chromosome 18". Genomics 13 (2): 484–6.
2、 "Entrez Gene: DSG2 desmoglein 2". mutations in DSG2 contribute to the development of ARVD/C.
3、Syrris, P., Ward, D., Asimaki, A., Evans, A., Sen-Chowdhry, S., Hughes, S. E., McKenna, W. J. Desmoglein-2 mutations in arrhythmogenic right ventricular cardiomyopathy: a genotype-phenotype characterization of familial disease. Europ. Heart J. 28: 581-588, 2007.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Desmoglein 1 + 2 antibody

Desmoglein 1 + 2 Mouse IgG1 DG3.10 Purified Bov, Hu, Ms, Rt C, ICC/IF, P, WB
50 µg / €300.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Desmoglein-2 Mouse IgG1 10G11 Purified Hu C, E, ICC/IF, P, WB
50 µg / €300.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Desmoglein-2 Mouse IgG1 G129 Supernatant Hu C, E, P, WB
5 ml / €270.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Immunohistochemistry-Paraffin: Desmoglein 2 Antibody [NBP1-59200] - Human colon stained with Rabbit Anti-Desmoglein 2 Antibody (5 ug/ml). Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Desmoglein-2 antibody

Sample (30 ug of whole cell lysate). A: 293T. B: H1299. C: Molt-4 . 7.5% SDS PAGE. TA308539 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Desmoglein-2 antibody

Western blot analysis of extracts from HeLa cells, using DSG2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Desmoglein-2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DSG2 (RC212294, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DSG2. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Desmoglein-2 (N-term) antibody

Western blot analysis of anti-DSG2 Antibody (N-term) in T47D cell line lysates (35ug/lane). DSG2 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Western blot (WB) analysis of Dsg2 antibody (Cat.-No.: AP21161PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Desmoglein-2 Mouse IgG1 G96 Supernatant Hu C, E, P, WB
5 ml / €270.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Desmoglein-2 Rabbit Serum Hu C, E, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Desmoglein-2 Mouse IgG1 6D8 Purified Hu C, IP, WB
0.2 mg / €510.00
  Acris Antibodies GmbH

Desmoglein-2 (Extracell. Dom.) antibody

Desmoglein-2 Mouse IgG1 6D8 Purified Hu C, ICC/IF, IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Desmoglein-2 Mouse IgG1 6D8 Purified Hu C, IP, WB
25 µg / €210.00
  Acris Antibodies GmbH

Desmoglein-2 antibody

Western blot analysis of extracts from HeLa cells, using DSG2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Desmoglein-2 antibody

Western blot analysis of extracts from HeLa cells, using DSG2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Desmoglein-2 antibody

Human Colon; Immunohistochemistry with Human Colon lysate tissue at an antibody concentration of 5.0ug/ml using anti-DSG2 antibody (ARP45198_P050); DSG2 antibody - N-terminal region (ARP45198_P050) in Human Colon cells using Immunohistochemistry Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

Desmoglein-2 antibody

Desmoglein-2 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Desmoglein-2 antibody

Desmoglein 2 Antibody  [10D2] Mouse IgG1 10D2 Purified Hu, Ms ICC/IF, IP, WB
0.1 ml / €400.00
  Immuquest

Desmoglein-2 antibody

Desmoglein 2 Antibody [7H9] Mouse IgG1 7H9 Purified Hu ICC/IF, WB
0.1 ml / €400.00
  Immuquest

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