Desmoglein-4 antibody
Principal name
Desmoglein-4 antibody
Alternative names for Desmoglein-4 antibody
DSG4, CDHF13, Cadherin family member 13
Ncbi ID
9606, NP_001127925, NP_001127925.1, NM_177986, NM_181564, NM_199490, NM_001134453
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C)
Background of Desmoglein-4 antibody
Desmoglein 4 (DSG4) is a component of intercellular desmosome junctions. DSG4 is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSG4 coordinates the transition from proliferation to differentiation in hair follicle keratinocytes. The essential role of desmoglein 4 in skin was established by identifying mutations in families with inherited hypotrichosis, as well as in the lanceolate hair mouse. The human desmoglein 4 gene (DSG4) demonstrates that it is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3. Defects in DSG4 are the cause of localized autosomal hypotrichosis (LAH). LAH is an autosomal recessive skin disorder. DSG4 is one of the target molecules recognized by autoantibodies in patients with pemphigus vulgaris. Pemphigus vulgaris is a potentially lethal skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP09539SU-N | Desmoglein-4 (472-590) antibody |
||||||
 |
Guinea Pig | Serum | Hu | C |
0.1 ml /
€380.00
|
||
| Acris Antibodies GmbH | |||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN214121 | DSG4 - human gene knockout kit via CRISPR |
||
|
Human | GFP-Puro |
1 kit /
€1,200.00
|
| OriGene Technologies, Inc. | |||
| KN214121BN | DSG4 - human gene knockout kit via CRISPR |
||
|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN214121LP | DSG4 - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN214121RB | DSG4 - human gene knockout kit via CRISPR |
||
|
Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Lysates
| Catalog No. | ||
|---|---|---|
| LY406073 | DSG4 overexpression lysate |
|
|
0.1 mg /
€480.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC226314L2V | Lenti ORF particles, DSG4 (mGFP-tagged)-Human desmoglein 4 (DSG4), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,140.00
|
|
| OriGene Technologies, Inc. | ||
| RC214121L2V | Lenti ORF particles, DSG4 (mGFP-tagged) - Human desmoglein 4 (DSG4), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,320.00
|
|
| OriGene Technologies, Inc. | ||
| RC226314L1V | Lenti ORF particles, DSG4 (Myc-DDK-tagged)-Human desmoglein 4 (DSG4), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,930.00
|
|
| OriGene Technologies, Inc. | ||
| RC214121L1V | Lenti ORF particles, DSG4 (Myc-DDK tagged) - Human desmoglein 4 (DSG4), transcript variant 2 , 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,180.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR220643L1V | Lenti ORF particles, Dsg4 (Myc-DDK-tagged) - Mouse desmoglein 4 (Dsg4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,650.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR208316L2V | Lenti ORF particles, Dsg4 (GFP-tagged ORF) - Rat desmoglein 4 (Dsg4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,180.00
|
|
| OriGene Technologies, Inc. | ||
| RR208316L1V | Lenti ORF particles, Dsg4 (Myc-DDK-tagged ORF) - Rat desmoglein 4 (Dsg4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,962.00
|
|
| OriGene Technologies, Inc. | ||
