Desmoglein-4 antibody

Principal name

Desmoglein-4 antibody

Alternative names for Desmoglein-4 antibody

DSG4, CDHF13, Cadherin family member 13

SwissProt ID

Q6W3B0 (Rat), Q7TMD7 (Mouse), Q86SJ6 (Human)

Gene ID

147409 (DSG4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Guinea Pig, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of Desmoglein-4 antibody

Desmoglein 4 (DSG4) is a component of intercellular desmosome junctions. DSG4 is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSG4 coordinates the transition from proliferation to differentiation in hair follicle keratinocytes. The essential role of desmoglein 4 in skin was established by identifying mutations in families with inherited hypotrichosis, as well as in the lanceolate hair mouse. The human desmoglein 4 gene (DSG4) demonstrates that it is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3. Defects in DSG4 are the cause of localized autosomal hypotrichosis (LAH). LAH is an autosomal recessive skin disorder. DSG4 is one of the target molecules recognized by autoantibodies in patients with pemphigus vulgaris. Pemphigus vulgaris is a potentially lethal skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Desmoglein-4 (472-590) antibody

Desmoglein-4 Guinea Pig Serum Hu C
0.1 ml / €370.00
  Acris Antibodies GmbH

Desmoglein-4 antibody

Desmoglein-4 Mouse IgG1 6E7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Desmoglein-4 antibody

Desmoglein-4 Rabbit Hu, Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Desmoglein-4 antibody

Western blot analysis of Desmoglein 4 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Desmoglein-4 antibody

Western blot analysis of Desmoglein 4 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Desmoglein-4 antibody

Western blot analysis of Desmoglein 4 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Desmoglein-4

Desmoglein-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Desmoglein-4

Desmoglein-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DSG4 overexpression lysate

DSG4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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