DGCR6L antibody

Principal name

DGCR6L antibody

Alternative names for DGCR6L antibody

DiGeorge syndrome critical region 6-like protein

SwissProt ID

Q9BY27 (Human)

Gene ID

85359 (DGCR6L)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of DGCR6L antibody

Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin-1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome; a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt’s lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.

General readings

Li,X., et al. (2010) Int. J. Biochem. Cell Biol. 42 (1), 70-79Pfuhl,T., et al. (2005) Hum. Genet. 117 (1), 70-80

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DGCR6L antibody

WB Suggested Anti-DGCR6L Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DGCR6L (Center) antibody

Western blot analysis of DGCR6L (arrow) using rabbit polyclonal DGCR6L Antibody (Center) (Cat. #AP51251PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DGCR6L gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DGCR6L antibody

Western Blot analysis of DGCR6L expression in transfected 293T cell line (H00085359-T01) by DGCR6L MaxPab polyclonal antibody.

Lane 1: DGCR6L transfected lysate(24.2 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

DGCR6L (C-term) antibody

Human Fetal Brain; WB Suggested Anti-DGCR6L Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Brain; DGCR6L antibody - C-terminal region (ARP60877_P050) in Human Fetal Brain cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

DGCR6L antibody

DGCR6L Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DGCR6L

DGCR6L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DGCR6L (1-220, His-tag)

DGCR6L Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

DGCR6L (1-220, His-tag)

DGCR6L Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

DGCR6L

DGCR6L Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DGCR6L

DGCR6L Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DGCR6L 293T Cell Transient Overexpression Lysate(Denatured)

DGCR6L 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

DGCR6L overexpression lysate

DGCR6L overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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