DIAPH2 antibody

Principal name

DIAPH2 antibody

Alternative names for DIAPH2 antibody

DIA, diaphanous homolog 2, Diaphanous-related formin-2, DRF

SwissProt ID

O60879 (Human), O70566 (Mouse)

Gene ID

1730 (DIAPH2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of DIAPH2 antibody

DIA-2 (also called DIA drome, Dia2, DIAPH2, Diaphanous 2, Diaphanous related formin 2, Diaphorase 2, DRF2, POF and POF2) may play a role in the development and normal function of the ovaries. Mutations of this gene have been linked to premature ovarian failure. Alternative splicing results in two protein isoforms. Furthermore, each splice variant undergoes additional splicing in the 3' UTR. Overall 4 splice variants have been described. DIA-2 is expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes and can be found from E16 in ovary and testis and during P6-P16 during differentiation of ovarian follicles. Isoform 1 is referred to as DIA-156, whereas isoform 2 is called DIA-12C.

General readings

Olsen, J.V., et al. Cell 127(3):635-648 (2006).
Olsen, J.V., et al. Cell 127(3):635-648 (2006).
Yasuda, S., et al. Nature 428(6984):767-771 (2004).
Gasman, S., et al. Nat. Cell Biol. 5(3):195-204 (2003).
Satoh, S., et al. J. Biol. Chem. 276(42):39290-39294 (2001).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DIAPH2 (Center) antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with DIAPH2 Antibody Cat.-No AP51260PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

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