Dickkopf-1 antibody

Principal name

Dickkopf-1 antibody

Alternative names for Dickkopf-1 antibody

DKK1, DKK-1, Dickkopf-related protein 1, SK

SwissProt ID

O54908 (Mouse), O94907 (Human)

Gene ID

22943 (DKK1), 13380

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Mky (Monkey), GP (Guinea Pig), Gt (Goat), Sh (Sheep), Bt (Bat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Dickkopf-1 antibody

DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis.

General readings

Fedi P, Bafico A, Nieto Soria A, Burgess WH, Miki T, Bottaro DP, Kraus MH, Aaronson SA. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem. 1999 Jul 2;274(27):19465-72.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dickkopf-1 (C-term) antibody

TA302464 (1µg/ml) staining of human bone marrow lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dickkopf-1 antibody

Host: Rabbit; Target Name: DKK1; Sample Tissue: PANC1 Whole Cell lysates; Antibody Dilution: 1.0 ug/mlDKK1 is supported by BioGPS gene expression data to be expressed in PANC1 Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Dickkopf-1 (1st Cytopl. Dom.) antibody

Anti-DKK1 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

Dickkopf-1 antibody

Anti-DKK1 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified GP, Gt, Hu, Rb, Sh
50 µg / €379.00
  OriGene Technologies, Inc.

Dickkopf-1 (N-term) antibody

Anti-DKK1 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Elephant, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

Dickkopf-1 antibody

Anti-DKK1 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Eq, Hu, Mky, Por, Rb
50 µg / €379.00
  OriGene Technologies, Inc.

Dickkopf-1 antibody

Western blot analysis using DKK1 antibody Cat.-No AM06319SU-N against HEK293 (Lane 1) and DKK1-hIgGFc transfected HEK293 cell lysate (Lane 2). Mouse IgG2b 2H2 Ascites Hu WB
0.1 ml / €360.00
  Acris Antibodies GmbH

Dickkopf-1 (C-term) antibody

Placenta: Formalin-Fixed Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Gt, Hst, Hu, Mky, Ms, Platypus, Por, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Dickkopf-1 (N-term) antibody

Western blot analysis of Dickkopf-1 Antibody (N-term) Cat.-No AP51269PU-N in T47D cell line lysates (35ug/lane). DKK1 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Dickkopf-1 antibody

Dickkopf-1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between DKK1 and CTNNB1 HeLa cells were stained with anti-DKK1 rabbit purified polyclonal 1:1200 and anti-CTNNB1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

DKK1 monoclonal antibody (M01), clone 4D4. Western Blot analysis of DKK1 expression in Jurkat ( Cat # L017V1 ). Mouse IgG2b 4D4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

DKK1 monoclonal antibody (M02), clone 1F5. Western Blot analysis of DKK1 expression in Jurkat ( Cat # L017V1 ). Mouse IgG2b 1F5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

DKK1 monoclonal antibody (M04), clone 3D9 Western Blot analysis of DKK1 expression in HeLa ( Cat # L013V1 ). Mouse IgG2b 3D9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

DKK1 monoclonal antibody (M05), clone 3G3 Western Blot analysis of DKK1 expression in HeLa ( Cat # L013V1 ). Mouse IgG2b 3G3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

DKK1 monoclonal antibody (M06), clone 4C10. Western Blot analysis of DKK1 expression in Raw 264.7 ( Cat # L024V1 ). Mouse IgG2b 4C10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

Dickkopf-1 Mouse IgG2a 4B10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

Immunoperoxidase of monoclonal antibody to DKK1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse IgG2b 2B12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

Dickkopf-1 Mouse IgG2b 3C2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dickkopf-1 antibody

DKK1 monoclonal antibody (M10), clone 1A3. Western Blot analysis of DKK1 expression in human lung cancer. Mouse IgG2a 1A3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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