Diphtheria toxin antibody

Principal name

Diphtheria toxin antibody

Alternative names for Diphtheria toxin antibody

Corynebacterium diphtheriae toxin

Available reactivities

Bac (Bacteria), Hu (Human)

Available hosts

Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), ELISA (capture) (E(capture)), Frozen Sections (C), Paraffin Sections (P)

Background of Diphtheria toxin antibody

Diphtheria toxin is a 58 kDa protein secreted by lysogenic strains of Corynebacterium diphtheriae. The toxin causes the disease diphtheria in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis. The mechanism of inhibition involves transfer of the ADP-ribose group of NAD to elongation factor-2 (EF-2), rendering EF-2 inactive. The catalysed reaction is as follows: NAD + + peptide diphthamide = nicotinamide + peptide N-(ADP-D-ribosyl)diphthamide The crystal structure of the diphtheria toxin homodimer has been determined to 2.5A resolution. The structure reveals a Y-shaped molecule of 3 domains, a catalytic domain (fragment A), whose fold is of the alpha + beta type; a transmembrane (TM) domain, which consists of 9 alpha-helices, 2 pairs of which may participate in pH-triggered membrane insertion and translocation; and a receptor-binding domain, which forms a flattened beta-barrel with a jelly-roll-like topology. The TM- and receptor binding-domains together constitute fragment B. Detection of Diphtheria toxin A subunit

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Diphtheria toxin (A subunit free + bound) antibody

Diphtheria toxin Mouse IgG1 178 Purified E
1 mg / €830.00
  Acris Antibodies GmbH

Diphtheria toxin antibody

Diphtheria toxin Mouse IgG1 817 Purified E
1 mg / €710.00
  Acris Antibodies GmbH

Diphtheria toxin (intact) antibody

Diphtheria toxin Mouse IgG1 8G1 Purified E, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Diphtheria toxin (A subunit) antibody

Diphtheria toxin Mouse IgG1 8G2 Purified E
0.1 mg / €530.00
  Acris Antibodies GmbH

Diphtheria toxin antibody

Diphtheria toxin Goat Ig Fraction E

Regular Price: 1 ml / €390.00

Special Price: 1 ml / €210.00

  Acris Antibodies GmbH

Diphtheria toxin antibody

Diphtheria toxin Goat Biotin E
1 ml / €400.00
  Acris Antibodies GmbH

Diphtheria toxin antibody

Diphtheria toxin Goat FITC E, ICC/IF
1 ml / €400.00
  Acris Antibodies GmbH

Diphtheria toxin antibody

Diphtheria toxin Goat HRP E
1 ml / €1,020.00
  Acris Antibodies GmbH

Diphtheria toxin (whole molecule) antibody

Diphtheria toxin Mouse IgG1 1H2 Purified E, E(detection)
1 mg / €310.00
  HyTest Ltd.

Diphtheria toxin (whole molecule) antibody

Diphtheria toxin Mouse IgG1 3B6 Purified E, E(capture)
1 mg / €310.00
  HyTest Ltd.

Diphtheria toxin (whole molecule) antibody

Diphtheria toxin Mouse IgG2b DiB4 Purified E, E(detection), WB
1 mg / €310.00
  HyTest Ltd.

Diphtheria toxin (whole molecule) antibody

Diphtheria toxin Mouse IgG2b DiD1 Purified E, E(detection), WB
1 mg / €310.00
  HyTest Ltd.

Diphtheria toxin (whole molecule) antibody

Diphtheria toxin Mouse IgG1 DiH1 Purified E, E(capture)
1 mg / €310.00
  HyTest Ltd.

Diphtheria toxin (free alpha + whole molec.) antibody

Diphtheria toxin Mouse IgG1 7F2 Purified E, E(detection)
1 mg / €310.00
  HyTest Ltd.

Diphtheria toxin (free alpha subunit) antibody

Diphtheria toxin Mouse IgG2a 8A4 Purified E, E(capture)
1 mg / €310.00
  HyTest Ltd.

15 Item(s)

per page
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