DIS3-like exonuclease 2 antibody

Principal name

DIS3-like exonuclease 2 antibody

Alternative names for DIS3-like exonuclease 2 antibody

DIS3L2, FAM6A, MGC42174

SwissProt ID

Q8CI75 (Mouse), Q8IYB7 (Human)

Gene ID

129563 (DIS3L2)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C), Enzyme Immunoassay (E)

Background of DIS3-like exonuclease 2 antibody

The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3’ processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.

General readings

Ota,T., (2004) Nat. Genet. 36 (1), 40-45

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DIS3-like exonuclease 2 antibody

WB Suggested Anti-MGC42174 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DIS3-like exonuclease 2 antibody

WB Suggested Anti-MGC42174 Antibody Titration: 1.25 ug/ml; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DIS3-like exonuclease 2 antibody

Western Blot analysis of DIS3L2 expression in transfected 293T cell line (H00129563-T01) by DIS3L2 MaxPab polyclonal antibody.

Lane 1: MGC42174 transfected lysate(68.09 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

DIS3-like exonuclease 2 antibody

DIS3-like exonuclease 2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

DIS3-like exonuclease 2 antibody

Human Heart; Rabbit Anti-MGC42174 Antibody. Catalog Number: ARP41145. Paraffin Embedded Tissue: Human Heart. Cellular Data: Myocardial cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; MGC42174 antibody - N-terminal region (ARP41145_T100) in Human Heart cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

DIS3-like exonuclease 2 antibody

Human Intestine; Rabbit Anti-MGC42174 Antibody. Catalog Number: ARP41146. Paraffin Embedded Tissue: Human Intestine. Cellular Data: Epithelial cells of intestinal villas. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; MGC42174 antibody - N-terminal region (ARP41146_T100) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

DIS3-like exonuclease 2 antibody

DIS3-like exonuclease 2 Rabbit Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

DIS3-like exonuclease 2 antibody

DIS3-like exonuclease 2 Rabbit Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

DIS3-like exonuclease 2 antibody

Immunohistochemistry-Paraffin: DIS3L2 Antibody [NBP1-84740] - Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DIS3-like exonuclease 2

DIS3-like exonuclease 2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DIS3-like exonuclease 2

DIS3-like exonuclease 2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DIS3-like exonuclease 2

DIS3-like exonuclease 2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DIS3L2 overexpression lysate

DIS3L2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

MGC42174 293T Cell Transient Overexpression Lysate(Denatured)

MGC42174 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

per page
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