Dishevelled-2 / DVL2 antibody

Principal name

Dishevelled-2 / DVL2 antibody

Alternative names for Dishevelled-2 / DVL2 antibody

DVL-2, DSH homolog 2, Segment polarity protein dishevelled homolog DVL-2

SwissProt ID

O14641 (Human), P51142 (Xenla), Q60838 (Mouse)

Gene ID

1856 (DVL2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Dishevelled-2 / DVL2 antibody

DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslatiol phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the sigl transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt sigling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslatiol phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the sigl transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt sigling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Inkster, B., et al. Neuroimage 53(3):908-917(2010).
Kikuchi, K., et al. EMBO J. 29(20):3470-3483(2010).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010).
Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010).
Gnad, T., et al. Mol. Cancer 9, 31 (2010).

4 Item(s)

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CRISPR

Catalog No. Species Donor Vector  

DVL2 - human gene knockout kit via CRISPR

DVL2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DVL2 - human gene knockout kit via CRISPR

DVL2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DVL2 - human gene knockout kit via CRISPR

DVL2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DVL2 - human gene knockout kit via CRISPR

DVL2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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