DISP1 / DISPA antibody

Principal name

DISP1 / DISPA antibody

Alternative names for DISP1 / DISPA antibody

Protein dispatched homolog 1

SwissProt ID

Q3TDN0 (Mouse), Q96F81 (Human)

Gene ID

84976 (DISP1), 68897 (Disp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of DISP1 / DISPA antibody

DISP1 functions in hedgehog (Hh) sigling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh sigl.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein sigls. Cells surrounding the source of a particular sigl respond in a graded manner according to the effective concentration of the sigl, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) sigling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.

General readings

Caspary T, Garcia-Garcia MJ, Huangfu D, et al. Mouse dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling. Curr. Biol. 2002; 12:1628-32.

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DISP1 / DISPA (C-term) antibody

  Goat Anti-Dispatched homolog 1 Antibody  
TA305822 (2.5ug/ml) staining of U87. Detected by immunofluorescence. Goat Aff - Purified Hu, Ms, Rt ICC/IF
0.1 mg / €325.00
  OriGene Technologies, Inc.

DISP1 / DISPA (N-term) antibody

  Rabbit Polyclonal DISP1 Antibody  
Western blot analysis of DISP1 in 3T3 cell lysate with DISP1 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DISP1 / DISPA antibody

  Rabbit Polyclonal Anti-DISP1 Antibody  
WB Suggested Anti-DISP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Small Intestine Rabbit IgG Purified Eq, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

DISP1 - human gene knockout kit via CRISPR

DISP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DISP1 - human gene knockout kit via CRISPR

DISP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DISP1 - human gene knockout kit via CRISPR

DISP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DISP1 - human gene knockout kit via CRISPR

DISP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Disp1 - mouse gene knockout kit via CRISPR

Disp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Disp1 - mouse gene knockout kit via CRISPR

Disp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Disp1 - mouse gene knockout kit via CRISPR

Disp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Disp1 - mouse gene knockout kit via CRISPR

Disp1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DISP1 (mGFP-tagged) - Human dispatched homolog 1 (Drosophila) (DISP1), 200 uL, >10^7 TU/mL

Lenti ORF particles, DISP1 (mGFP-tagged) - Human dispatched homolog 1 (Drosophila) (DISP1), 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, DISP1 (Myc-DDK tagged) - Human dispatched homolog 1 (Drosophila) (DISP1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, DISP1 (Myc-DDK tagged) - Human dispatched homolog 1 (Drosophila) (DISP1) , 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Disp1 (GFP-tagged) - Mouse dispatched homolog 1 (Drosophila) (Disp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Disp1 (GFP-tagged) - Mouse dispatched homolog 1 (Drosophila) (Disp1), 200 uL, >10^7 TU/mL  
200 µl / €2,470.00
  OriGene Technologies, Inc.

Lenti ORF particles, Disp1 (Myc-DDK-tagged) - Mouse dispatched homolog 1 (Drosophila) (Disp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Disp1 (Myc-DDK-tagged) - Mouse dispatched homolog 1 (Drosophila) (Disp1), 200 uL, >10^7 TU/mL  
200 µl / €2,230.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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