DISP2 / DISPB antibody

Principal name

DISP2 / DISPB antibody

Alternative names for DISP2 / DISPB antibody

Protein dispatched homolog 2, KIAA1742

SwissProt ID

A7MBM2 (Human), Q8CIP5 (Mouse)

Gene ID

85455 (DISP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of DISP2 / DISPB antibody

Disp2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the Disp proteins have been implicated in these pathways. Recently, it has been shown that Disp2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased Disp2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by Disp2 mutants. At least two isoforms of Disp2 are known to exist. This Disp2 antibody is predicted to not cross-react with Disp1 or Disp3.

General readings

Katoh Y and Katoh M. Identification and characterization of DISP3 gene in silico. Int. J. Oncol. 2005; 26:551-6.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DISP2 / DISPB (C-term) antibody

Western blot analysis of Disp2 in rat brain tissue lysate with Disp2 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DISP2 / DISPB (N-term) antibody

Immunohistochemistry of DISP2 in human small intestine tissue with DISP2 antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

DISP2 / DISPB Control Peptide

DISP2 / DISPB
50 µg / €160.00
  Acris Antibodies GmbH

DISP2 / DISPB (N-term) Control Peptide

DISP2 / DISPB
50 µg / €160.00
  Acris Antibodies GmbH

4 Item(s)

per page
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