DLG2 / PSD93 antibody

Principal name

DLG2 / PSD93 antibody

Alternative names for DLG2 / PSD93 antibody

Disks large homolog 2, PSD-93, Chapsyn-110, Postsynaptic density protein PSD-93, Channel-associated protein of synapse-110

SwissProt ID

Q15700 (Human), Q63622 (Rat), Q91XM9 (Mouse)

Gene ID

1740 (DLG2), 64053 (Dlg2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of DLG2 / PSD93 antibody

Chapsyn 110 (also known as PSD93 and DLG2) is a PDZ containing domain protein that is also a member of the membrane-associated guanylate kise (MAGUK) family of multi-domain adaptor proteins. PDZ domains are conserved protein domains of about 90 amino acids involved in protein–protein recognition, protein targeting and assembly of multi-protein complexes. The me PDZ derives from the first three proteins in which these domains were identified: PSD-95 (a 95 kDa protein involved in sigling at the post-syptic density), DLG (the Drosophila melanogaster Discs Large protein) and ZO-1 (the zonula occludens 1 protein involved in maintence of epithelial polarity). MAGUKs are scaffolding proteins that comprise several modular protein binding motifs including one or more PDZ domains, a Src homology 3 (SH3) domain, and a catalytically ictive guanylate kise-like domain. The multidomain ture of PDZ-containing proteins ebles them to interact with multiple binding partners and hence organize larger sigling protein complexes. Indeed, Chapsyn 110 has been shown to participate in the postsyptic density, a dedicated structure formed in postsyptic nerve termils that includes a specialized assembly of ion channels, receptors and sigling molecules that are involved in information processing and the modulation of syptic plasticity.

General readings

Kimura,K., (2006) Genome Res. 16 (1), 55-65

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DLG2 / PSD93 antibody

Adult rat brain hippocampus immunohistochemistry. Mouse IgG1 N18/30 Supernatant Hu, Ms, Rt C, ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

DLG2 / PSD93 antibody

Adult rat brain cerebellum immunohistochemistry. Mouse IgG2a N18/28 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

DLG2 / PSD93 antibody

Adult rat brain hippocampus immunohistochemistry. Mouse IgG1 N18/30 Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

DLG2 / PSD93 antibody

Adult rat brain cerebellum immunohistochemistry. Mouse IgG2a N18/28 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

DLG2 / PSD93 (1-852) antibody

  Mouse Monoclonal Anti-Chapsyn-110 Antibody  
Western blot analysis of Chapsyn-110 in rat brain membrane lysates using a 1:1000 dilution of the antibody Mouse IgG1 S18-30 Purified Ms, Rt C, ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DLG2 / PSD93 antibody

  Rabbit polyclonal Anti-Chapsyn 110  
Western blot analysis of rat brain membranes: 1. Anti-Chapsyn 110 antibody , (1:1000). 2. Anti-Chapsyn 110 antibody, preincubated with the control fusion protein antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

DLG2 / PSD93 antibody

  Rabbit Polyclonal Anti-DLG2 Antibody  
WB Suggested Anti-DLG2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

DLG2 / PSD93 antibody

  Rabbit Polyclonal Anti-DLG2 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (DLG2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

DLG2 - human gene knockout kit via CRISPR

DLG2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DLG2 - human gene knockout kit via CRISPR

DLG2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DLG2 - human gene knockout kit via CRISPR

DLG2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DLG2 - human gene knockout kit via CRISPR

DLG2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DLG2 / PSD93 (transcript variant 4)

  Recombinant protein of human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 4  
DLG2 / PSD93 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

DLG2 overexpression lysate

DLG2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

DLG2 overexpression lysate

DLG2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DLG2 (mGFP-tagged) - Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, DLG2 (mGFP-tagged) - Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,010.00
  OriGene Technologies, Inc.

Lenti ORF particles, DLG2 (mGFP-tagged)-Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DLG2 (mGFP-tagged)-Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,840.00
  OriGene Technologies, Inc.

Lenti ORF particles, DLG2 (Myc-DDK tagged) - Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, DLG2 (Myc-DDK tagged) - Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,810.00
  OriGene Technologies, Inc.

Lenti ORF particles, DLG2 (Myc-DDK-tagged)-Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DLG2 (Myc-DDK-tagged)-Human discs, large homolog 2 (Drosophila) (DLG2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,660.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dlg2 (GFP-tagged ORF) - Rat discs, large homolog 2 (Drosophila) (Dlg2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dlg2 (GFP-tagged ORF) - Rat discs, large homolog 2 (Drosophila) (Dlg2), 200 uL, >10^7 TU/mL  
200 µl / €1,580.00
  OriGene Technologies, Inc.

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