DLGAP3 antibody

Principal name

DLGAP3 antibody

Alternative names for DLGAP3 antibody

DAP3, DAP-3, SAPAP3, Disks large-associated protein 3, SAP90/PSD-95-associated protein 3, PSD-95/SAP90-binding protein 3

SwissProt ID

O95886 (Human), P97838 (Rat), Q6PFD5 (Mouse)

Gene ID

58512 (DLGAP3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C)

Background of DLGAP3 antibody

SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.

5 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DLGAP3 antibody

Western blot analysis of SAPAP3 in rat brain tissue lysate with SAPAP3 antibody at (A) 1 (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DLGAP3 Control Peptide

DLGAP3
50 µg / €160.00
  Acris Antibodies GmbH

DLGAP3 antibody

Immunohistochemical staining of human brain tissue using DLGAP3 polyclonal antibody ( Cat # PAB13019 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

DLGAP3 antibody

Immunohistochemistry-Paraffin: DLGAP3 Antibody [NBP1-90601] Immunohistochemical staining of human kidney shows moderate positivity in cells in glomeruli. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

DLGAP3 overexpression lysate

DLGAP3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

5 Item(s)

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