DMC1 / LIM15 antibody

Principal name

DMC1 / LIM15 antibody

Alternative names for DMC1 / LIM15 antibody

DMC1H, Meiotic recombination protein DMC1/LIM15 homolog

SwissProt ID

Q14565 (Human), Q61880 (Mouse)

Gene ID

11144 (DMC1)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F)

Background of DMC1 / LIM15 antibody

DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA. The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway. Rad51 is essential for mitotic and meiotic recombination, and its mutation in yeast and mammalian cells results in chromosome loss. Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination. Rad52 is thought to be involved in an early stage of Rad51-mediated recombination. Additional proteins involved in the pathway include Nibrin and Dmc1. Nibrin, which complexes with Mre11 and Rad50, is absent in Nijemegen breakage syndrome (NBS) patients. Dmc1 is specifically involved in meiotic recombination. An alternative spliced form of Dmc1, designated Dmc1-D, is deleted for a region between the two motifs involved in nucleotide binding. The alternatively spliced Dmc1-D transcript is detected in both male and female germ cells, indicating that the encoded protein may have a role in mammalian genetic recombination in meiosis.

General readings

Volodin, A.A. et al., J. Biol. Chem. 284 (3): 1495-1504 (2009)
Hikiba, J. et al., FEBS J. 276 (2): 457-465 (2009)
Hikiba, J. et al., Nucleic Acids Res. 36 (12): 4181-4190 (2008)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DMC1 / LIM15 antibody

Western Blot: DMC1 Antibody (1D12/4) - Analysis of DMC1 on human testis. Mouse IgG1 1D12/4 Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DMC1 / LIM15 antibody

Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308368 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DMC1 / LIM15 antibody

Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308786 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DMC1 / LIM15 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue using DMC1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

DMC1 / LIM15 antibody

Western blot analysis on HeLa cell lysate using BARD1 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DMC1 / LIM15 (N-term) antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with DMC1 antibody (N-term) Cat.-No AP51277PU-N, followed by peroxidase-conjugated secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DMC1 / LIM15 antibody

DMC1 / LIM15 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

DMC1 / LIM15 antibody

DMC1 / LIM15 Mouse IgG2b 4E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DMC1 / LIM15 antibody

DMC1 monoclonal antibody (M10), clone 4A10. Western Blot analysis of DMC1 expression in Hela NE(Cat # L013V3 ). Mouse IgG2a 4A10 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DMC1 / LIM15 antibody

Western blot detection of DMC1 ( 37 kDa ) from mouse testes using DMC1 monoclonal antibody, clone 1D12/4 ( Cat #MAB2349 ) ( 1 : 1000 ). Mouse IgG1 1D12/4 Hu, Ms WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

DMC1 / LIM15 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using DMC1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €205.00
  Assay Biotech

DMC1 / LIM15 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using DMC1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €310.00
  Assay Biotech

DMC1 / LIM15 antibody

DMC1 / LIM15 Mouse IgG1 1D12/4 Ascites Hu, Ms WB
25 µl / €160.00
  Novus Biologicals Inc.

DMC1 / LIM15 antibody

DMC1 / LIM15 Mouse IgG2a 2H12/4 Bov, Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

DMC1 / LIM15 antibody

DMC1 / LIM15 Mouse IgG2a 5B10/2 Purified Hu IP, WB
0.1 mg / €320.00
  Novus Biologicals Inc.

DMC1 / LIM15 antibody

Western Blot: DMC1 Antibody [NBP1-32048]-  (30 ug of whole cell lysate) A: Raji 10% SDS PAGE diluted at 1:1000 Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

DMC1 / LIM15 antibody

Immunohistochemistry: DMC1 Antibody [NBP1-33688] - Immunohistochemical analysis of DMC1 on paraffin-embedded CaI27 xenograft, using NBP1-33688. Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

DMC1 / LIM15 antibody

Immunohistochemistry-Paraffin: DMC1 Antibody [NBP1-82838] - Immunohistochemical staining of human testis shows strong nuclear positivity in subsets of cells in ductus seminiferus. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DMC1 / LIM15

DMC1 / LIM15 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

DMC1 / LIM15

DMC1 / LIM15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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