DNA adenine methylase antibody

Principal name

DNA adenine methylase antibody

Alternative names for DNA adenine methylase antibody

DAM, Deoxyadenosyl-methyltransferase, DNA adenine methyltransferase

SwissProt ID

O33844 (Trepa), P0AEE8 (Ecoli), P0AEE9 (Eco57), P0C6Q8 (Vibch)

Gene ID

947893 (dam)

Ncbi ID


Available reactivities

Bac (Bacteria)

Available hosts


Available applications

Western blot / Immunoblot (WB)

Background of DNA adenine methylase antibody

DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence); (ii) methyl-directed mismatch repair; (iii) control of transposition of certain transposable DNA elements; and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science; 284:967-970; 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulent.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DNA adenine methylase antibody

DNA adenine methylase Mouse IgG1 RB1 Purified Bac WB
0.1 mg / €370.00
  OriGene Technologies GmbH

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per page
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