DNA polymerase beta antibody

Principal name

DNA polymerase beta antibody

Alternative names for DNA polymerase beta antibody

POLB

SwissProt ID

O57383 (Xenla), P06746 (Human), P06766 (Rat), Q27958 (Bovin), Q8K409 (Mouse)

Gene ID

5423 (POLB), 29240 (Polb), 18970

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Hst (Hamster), Chk (Chicken), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of DNA polymerase beta antibody

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol α, β, δ and ε are involved in DNA replication and repair. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits—p125, which interacts with the sliding DNA clamp protein PCNA, and p50. The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol ζ is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol θ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DNA polymerase beta antibody

  POLB Rabbit Polyclonal Antibody  
Western blot analysis of extracts of K562 cell lines, using POLB antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

DNA polymerase beta antibody

  Rabbit polyclonal DNA Polymerase ß antibody  
Western blot analysis of extracts from NIH/3T3 cells, using DNA Polymerase ß antibody (#TA311651).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DNA polymerase beta antibody

  Rabbit polyclonal anti-POLB antibody  
Western Blot of Rabbit Anti-POLß (DNA polymerase beta) Antibody (TA319428). Lane 1: LN428 FLAG POLß (control). Lane 2: A172. Load: 35 µg per lane. Primary antibody: POLß antibody at 1:2000 for overnight at 4°C. Secondary antibody: IRDye800™ goat anti-rabbit at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: ~40 kDa, ~40 kDa. Other band(s): unknown band ~75 kDd. Rabbit IgG Purified Hu E, WB
0.1 mg / €313.00
  OriGene Technologies, Inc.

DNA polymerase beta antibody

  Rabbit Polyclonal DNA Polymerase beta Antibody  
Western blot analysis on NIH-3T3 cell lysate using DNA Polymerase beta Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DNA polymerase beta antibody

  Rabbit Polyclonal Anti-POLB Antibody  
WB Suggested Anti-POLB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

DNA polymerase beta antibody

Immunohistochemical analysis in paraffin-embedded human breast carcinoma tissue using DNA polymerase beta Antibody Cat.-No AP06087PU-N. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

DNA polymerase beta antibody

Figure 1. Formalin fixed paraffin embedded human testis stained with DNA polymerase beta antibody DM319. Mouse IgG2a 61 Purified Hu P, WB
1 ml / €770.00
  Acris Antibodies GmbH

DNA polymerase beta antibody

Figure 1. Formalin fixed paraffin embedded human testis stained with DNA polymerase beta antibody DM319. Mouse IgG2a 61 Purified Hu P, WB
0.5 ml / €500.00
  Acris Antibodies GmbH

DNA polymerase beta antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using DNA Polymerase beta Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

DNA polymerase beta antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using DNA Polymerase beta Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Polb - mouse gene knockout kit via CRISPR

Polb - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Polb - mouse gene knockout kit via CRISPR

Polb - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Polb - mouse gene knockout kit via CRISPR

Polb - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Polb - mouse gene knockout kit via CRISPR

Polb - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DNA polymerase beta

  Recombinant protein of human polymerase (DNA directed), beta (POLB)  
DNA polymerase beta Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

DNA polymerase beta (1-335, His-tag)

DNA polymerase beta Human Purified > 90 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

DNA polymerase beta (1-335, His-tag)

DNA polymerase beta Human Purified > 90 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

POLB overexpression lysate

POLB overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

POLB-knockout Cell lysate

POLB-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Polb (GFP-tagged) - Mouse polymerase (DNA directed), beta (Polb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Polb (GFP-tagged) - Mouse polymerase (DNA directed), beta (Polb), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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