DNAJA3 / TID1 antibody

Principal name

DNAJA3 / TID1 antibody

Alternative names for DNAJA3 / TID1 antibody

hTid-1, HCA57, DnaJ homolog subfamily A member 3 mitochondrial, umorous imaginal discs protein Tid56 homolog, DnaJ protein Tid-1, Hepatocellular carcinoma-associated antigen 57

SwissProt ID

Q96EY1 (Human), Q99M87 (Mouse)

Gene ID

9093 (DNAJA3), 83945 (Dnaja3)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of DNAJA3 / TID1 antibody

TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localized splice variants of human Tid1 designated hTid1S and hTid1L. These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70. They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity. Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha. A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis. Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected. It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities. Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.

General readings

Qian, J., et al. Gastroenterology 138(4):1418-1428 (2010).
Kurzik-Dumke, U., et al. J Transl Med 8, 58 (2010).
Linnoila, J., et al. Neuron 60(4):625-641 (2008).
Kurzik-Dumke, U., et al. Int. J. Mol. Med. 21(1):19-31 (2008)
Kurzik-Dumke, U., et al. Cell. Signal. 19(9):1973-1985 (2007).

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DNAJA3 / TID1 antibody

  Rabbit Polyclonal Anti-DNAJA3 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (DNAJA3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

DNAJA3 / TID1 (C-term) antibody

Skeletal muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

DNAJA3 / TID1 (N-term) antibody

Western blot analysis of DNAJA3 / TID1 Antibody (N-term) Cat.-No AP51285PU-N in Hela cell line lysates (35ug/lane). This demonstrates the DNAJA3 antibody detected the DNAJA3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DNAJA3 / TID1 antibody

Immunofluorescence of purified MaxPab antibody to DNAJA3 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

DNAJA3 / TID1 antibody

Immunofluorescence of purified MaxPab antibody to DNAJA3 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

DNAJA3 / TID1 antibody

DNAJA3 / TID1 Rabbit Hu, Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

Dnaja3 - mouse gene knockout kit via CRISPR

Dnaja3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dnaja3 - mouse gene knockout kit via CRISPR

Dnaja3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DNAJA3 / TID1 (transcript variant 1)

  Purified recombinant protein of Homo sapiens DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 1  
DNAJA3 / TID1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DNAJA3 / TID1

DNAJA3 / TID1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

DNAJA3 / TID1

DNAJA3 / TID1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DNAJA3 / TID1

DNAJA3 / TID1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DNAJA3 (mGFP-tagged) - Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, DNAJA3 (mGFP-tagged) - Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Lenti ORF particles, DNAJA3 (mGFP-tagged)-Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DNAJA3 (mGFP-tagged)-Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, DNAJA3 (Myc-DDK tagged) - Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, DNAJA3 (Myc-DDK tagged) - Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €980.00
  OriGene Technologies, Inc.

Lenti ORF particles, DNAJA3 (Myc-DDK-tagged)-Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DNAJA3 (Myc-DDK-tagged)-Human DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dnaja3 (GFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dnaja3 (GFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dnaja3 (GFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dnaja3 (GFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dnaja3 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dnaja3 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €980.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dnaja3 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dnaja3 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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